Results 51 to 60 of about 2,449,966 (235)

Metabolic alterations in experimental models of depression [PDF]

open access: yes, 2016
Introduction: Major depressive disorder is one of the most prevalent psychiatric disorders and is associated with a severe impact on the personal functioning, thus with incurring significant direct and indirect costs.
Ionescu, Ecaterina   +7 more
core   +4 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

open access: yesAdvanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv   +10 more
wiley   +1 more source

Cushing′s syndrome: Stepwise approach to diagnosis

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
The projected prevalence of Cushing′s syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2-2% and it may no longer be considered as an orphan disease (2-3 cases/million/year).
Anurag R Lila   +5 more
doaj   +1 more source

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao   +13 more
wiley   +1 more source

Lipoprotein particles in patients with pediatric Cushing disease and possible cardiovascular risks. [PDF]

open access: yes, 2019
BackgroundCardiovascular (CV) complications are the most significant cause of mortality in adults with Cushing disease (CD); little is known about CV risk factors in children with CD.
Belyavskaya, Elena   +10 more
core  

Subclinical Cushing's syndrome in populations at risk [PDF]

open access: yes, 2007
Based on autopsy studies, adrenal masses are among the most common tumors in humans. Endogenous Cushing's syndrome (CS) is unusual and adrenal adenomas account for 10% of all cases of CS.
Caetano, Maria Silvia S.   +2 more
core   +2 more sources

Management of post‐implant fibrous dysplasia in the maxilla: A case study

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Fibrous dysplasia is generally rare, and even rarer in older adults. Special care is needed when altering the alveolar bone in these cases, especially if an implant is involved. This case study highlights such a scenario. Methods This case study details the experience of a 63‐year‐old African American female who presented with a ...
Yousef Taha Y. Amrou   +4 more
wiley   +1 more source

Pediatric Cushing′s disease: Management Issues

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Cushing′s disease (CD), caused by an ACTH-secreting pituitary corticotroph adenoma, is the commonest cause of Cushing syndrome in children over 5 years of age.
Martin O Savage, Helen L Storr
doaj   +1 more source

A Comparison of Regional Decisions for Doses and Administrations of New Drugs: Concordance, Discordance, and Dependencies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Regional differences in approved drug dosages and administration are shaped by complex factors, including clinical data, prior regulatory decisions, and region‐specific considerations. This study investigated how such factors are associated with variations in approved doses across the United States Food and Drug Administration (FDA), European Medicines
Sachiko Mita, Shunsuke Ono
wiley   +1 more source

Nelson′s syndrome presenting as bilateral oculomotor palsy

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Nelson′s syndrome refers to a clinical spectrum arising from progressive enlargement of pituitary adenoma and elevated adrenocorticotrophic hormone after total bilateral adrenalectomy for Cushing′s disease comprising of hyperpigmentation, visual field ...
Abhay Gundgurthi   +6 more
doaj   +1 more source

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