Results 191 to 200 of about 16,280 (231)
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JAMA, 2023
ImportanceCushing syndrome is defined as a prolonged increase in plasma cortisol levels that is not due to a physiological etiology. Although the most frequent cause of Cushing syndrome is exogenous steroid use, the estimated incidence of Cushing syndrome due to endogenous overproduction of cortisol ranges from 2 to 8 per million people annually ...
Martin, Reincke, Maria, Fleseriu
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ImportanceCushing syndrome is defined as a prolonged increase in plasma cortisol levels that is not due to a physiological etiology. Although the most frequent cause of Cushing syndrome is exogenous steroid use, the estimated incidence of Cushing syndrome due to endogenous overproduction of cortisol ranges from 2 to 8 per million people annually ...
Martin, Reincke, Maria, Fleseriu
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The Indian Journal of Pediatrics, 1997
Endogenous Cushing's Syndrome (CS) is a relatively uncommon disease in children. The etiology is more often a primary adrenal cause in infants and younger children, and corticotroph adenoma in older ones. Diagnostic evaluation must be stepwise and methodical, aimed at first confirming the presence of the disease, and then looking for the etiology.
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Endogenous Cushing's Syndrome (CS) is a relatively uncommon disease in children. The etiology is more often a primary adrenal cause in infants and younger children, and corticotroph adenoma in older ones. Diagnostic evaluation must be stepwise and methodical, aimed at first confirming the presence of the disease, and then looking for the etiology.
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Clinics in Endocrinology and Metabolism, 1985
Cushing's syndrome remains one of the most challenging problems in clinical endocrinology. Cushing's disease is caused in the majority of cases by basophil pituitary microadenomas which may be successfully treated by trans-sphenoidal hypophysectomy.
T A, Howlett, L H, Rees, G M, Besser
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Cushing's syndrome remains one of the most challenging problems in clinical endocrinology. Cushing's disease is caused in the majority of cases by basophil pituitary microadenomas which may be successfully treated by trans-sphenoidal hypophysectomy.
T A, Howlett, L H, Rees, G M, Besser
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The Lancet, 2015
Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's syndrome, including debilitating morbidities and increased mortality. Genetic and molecular mechanisms responsible for excess cortisol secretion by primary adrenal lesions and adrenocorticotropic hormone (ACTH) secretion from corticotroph or ectopic tumours have ...
Lacroix, A +3 more
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Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's syndrome, including debilitating morbidities and increased mortality. Genetic and molecular mechanisms responsible for excess cortisol secretion by primary adrenal lesions and adrenocorticotropic hormone (ACTH) secretion from corticotroph or ectopic tumours have ...
Lacroix, A +3 more
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Journal of Surgical Oncology, 2012
AbstractCushing's syndrome (CS) results from prolonged exposure to elevated endogenous cortisol. Majority of cases are caused by ACTH, pituitary, or ectopic origin. Primary adrenal hypersecretion is 15–20% caused by adenomas, carcinomas (ACC), and rarely by nodular adrenocortical disease. CS presents with all typical features.
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AbstractCushing's syndrome (CS) results from prolonged exposure to elevated endogenous cortisol. Majority of cases are caused by ACTH, pituitary, or ectopic origin. Primary adrenal hypersecretion is 15–20% caused by adenomas, carcinomas (ACC), and rarely by nodular adrenocortical disease. CS presents with all typical features.
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Subclinical Cushing’s syndrome
Best Practice & Research Clinical Endocrinology & Metabolism, 2012The routine use of abdominal procedure has significantly increased the incidental finding of adrenal masses. The prevalence of these tumors, commonly defined as adrenal incidentalomas, ranges between 2-3% in autopsy and 4% in radiological series, reaching 5-8% in oncological studies and increasing with patients age. Although clinically silent, in 5-20%
De Leo M +3 more
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New England Journal of Medicine, 1995
Cushing's syndrome is usually caused by the secretion of corticotropin or cortisol by a pituitary or adrenal tumor, respectively, or by ectopic secretion of corticotropin. It is possible to determine the specific abnormality in most patients, but it can sometimes be difficult to decide whether the patient has hypercortisolism and whether it is primary ...
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Cushing's syndrome is usually caused by the secretion of corticotropin or cortisol by a pituitary or adrenal tumor, respectively, or by ectopic secretion of corticotropin. It is possible to determine the specific abnormality in most patients, but it can sometimes be difficult to decide whether the patient has hypercortisolism and whether it is primary ...
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Pediatric Clinics of North America, 1990
The 10 years since this journal's last review of CS have seen extraordinary advances in our understanding of many aspects of its causes, diagnosis, and treatment. The spectrum of what are now called the Cushing syndromes has expanded considerably to include CD, multiple sources of ectopic ACTH secretion, and an apparent autoimmune cause.
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The 10 years since this journal's last review of CS have seen extraordinary advances in our understanding of many aspects of its causes, diagnosis, and treatment. The spectrum of what are now called the Cushing syndromes has expanded considerably to include CD, multiple sources of ectopic ACTH secretion, and an apparent autoimmune cause.
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Androgens in Cushing’s Syndrome
2019Although polycystic ovary syndrome (PCOS) is the most common androgen excess disorder, screening for Cushing's Syndrome (CS) should be considered in women with PCOS phenotype, particularly if they are also affected by other disturbances that increase their pretest probability (e.g., osteoporosis/bone fractures).
Arnaldi G., Martino M.
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Cushing's syndrome in pregnancy
International Journal of Gynecology & Obstetrics, 1982Abstract A diagnosis of Cushing's syndrome due to an adrenal adenoma was made at 32 weeks of gestation in a 26-year-old woman. Of particular interest were the very low levels of urinary estriol. At 36 weeks of gestation she spontaneously ruptured the membranes and delivered a 1.64 kg small-for-gestational-age male infant who was noted to have a minor
H, Khakoo +3 more
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