Results 51 to 60 of about 30,434 (264)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Variations in the Shape of Atrioventricular Cusps
Introduction: The right and the left atria of the human heart communicate with the right and left ventricle through the respective orifices. These orifices are guarded by atrioventricular valves.
Parmatma P Mishra +3 more
doaj +1 more source
ULTRA LOW FREQUENCY EMISSIONS RANGING FROM 0.1 TO 3 Hz IN CIRCUMPOLAR AREAS
We examine the characteristics of oscillations of two types in the high-frequency edge of the ULF range (0.1–3 Hz), serpentine emission (SE), and discrete frequency dispersed signals (DS).
A.S. Potapov +2 more
doaj +1 more source
Cusp summations and cusp relations of simple quad lenses [PDF]
We review five often used quad lens models, each of which has analytical solutions and can produce four images at most. Each lens model has two parameters, including one that describes the intensity of non-dimensional mass density, and the other one that describes the deviation from the circular lens. In our recent work, we have found that the cusp and
Chu, Zhe, Li, G. L., Lin, W. P.
openaire +2 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Given the paramount impacts of COVID-19 on people’s lives in the capital of the UK, London, it was foreseeable that the city’s crime patterns would have undergone significant transformations, especially during lockdown periods. This study aims to testify
Rui Wang, Yijing Li
doaj +1 more source

