Results 61 to 70 of about 625,134 (279)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Magnification Cross Sections for the Elliptic Umbilic Caustic Surface
Universe, 2019 In gravitational lensing, magnification cross sections characterize the probability that a light source will have magnification greater than some fixed value, which is useful in a variety of applications. The (area) cross section is known to scale as
Amir B. Aazami +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Cusp Singularities in the Magnetization Curve of Frustrated Kondo Necklace Model [PDF]
, 2002 Magnetization processes of frustrated Kondo necklace model are studied by means of a density matrix renormalization group (DMRG) method and an elementary band theory based on a bond-operator formalism.
Takahiro Yamamoto +3 more
semanticscholar +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Generalized Antiorthotomics of (n, m)-Cusp Curves
MathematicsIn optics, light rays emitted from a light source form a wavefront (orthotomic) upon reflection by a mirror. The mirror is referred to as an antiorthotomic of the orthotomic.
Qiming Zhao +3 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Quantization on the Ideal Boundary and the Finite Widths of Resonances
Quantum ReportsConformal field theory is quantized on the ideal boundary of a Riemann surface, and the effect on the widths of the resonances of the quantum states is evaluated.
Simon Davis
doaj +1 more source
Quantum caustics and the hierarchy of light cones in quenched spin chains
Physical Review Research, 2019 We show that the light conelike structures that form in spin chains after a quench are quantum caustics. Their natural description is in terms of catastrophe theory and this implies (1) a hierarchy of light cone structures corresponding to the different ...
W. Kirkby, J. Mumford, D. H. J. O'Dell
doaj +1 more source