Results 41 to 50 of about 98,500 (263)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Tsuchihashi's cusp singularities are Buchsbaum singularities

Tohoku Mathematical Journal, 1984
A Noetherian local ring \(A\) is said to be Buchsbaum if the difference \(\text{length}(A/I)-\text{mult}(I,A)\), defined for any ideal \(I\) generated by a system of parameters, is independent of \(I\). A Cohen-Macaulay ring is Buchsbaum; in fact, \(A\) is Cohen-Macaulay if and only if the above difference is zero for all \(I\). \textit{H. Tsuchihashi}
openaire   +2 more sources

Magnetic local time dependency on cusp ion velocity dispersions in the mid-altitude cusp [PDF]

, 2001
Observations of cusp ion velocity dispersions made by the TIMAS instrument on the Polar spacecraft in the mid-altitude cusp during intervals of northward interplanetary magnetic field (IMF) reveal a clear ordering with magnetic local time (MLT).
Krauklis, I, Coates, AJ, Peterson, WK
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Probing the dynamics of stringy flux tubes with large R-charge

Journal of High Energy Physics
We study the generalized cusp anomalous dimension, or quark-antiquark potential on the three-sphere, in the presence of a large R-charge L and at strong coupling.
Davide Bonomi, Valentina Forini, Valentina Giangreco M. Puletti, Luca Griguolo, Domenico Seminara   +4 more
doaj   +1 more source

Self-similar cuspidal formation by runaway thermocapillary forces in thin liquid films

New Journal of Physics, 2019
Many physical systems give rise to dynamical behavior leading to cuspidal shapes which represent a singularity of the governing equation. The cusp tip often exhibits self-similarity as well, indicative of scaling symmetry invariant in time up to a change
Chengzhe Zhou, Sandra M Troian
doaj   +1 more source

Cusp Singularities in Boundary-Driven Diffusive Systems [PDF]

Journal of Statistical Physics, 2013
Boundary driven diffusive systems describe a broad range of transport phenomena. We study large deviations of the density profile in these systems, using numerical and analytical methods. We find that the large deviation may be non-differentiable, a phenomenon that is unique to non-equilibrium systems, and discuss the types of models which display such
Bunin, Guy, Kafri, Yariv, Podolsky, Daniel   +2 more
openaire   +2 more sources

hpcng/singularity: Singularity 3.7.3

, 2021
Singularity 3.7.3 is a security release. We recommend all users upgrade to this version. Security Related Fixes CVE-2021-29136: A dependency used by Singularity to extract docker/OCI image layers can be tricked into modifying host files by creating a ...
cclerget, Ian Kaneshiro, David Godlove, David Trudgian, Michael Bauer, Gregory M. Kurtzer   +5 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source