Results 1 to 10 of about 1,586 (155)

Blood cardioplegia or custodiol for myocardial protection during valvular or aortic surgery: a propensity score adjusted comparison [PDF]

Journal of Cardiothoracic Surgery
Background There is no solid evidence on the clinical benefits of blood cardioplegia or Custodiol™ in procedures other than coronary artery bypass grafting.
Manuel Carnero- Alcazar, Lourdes Montero- Cruces, Rosa Beltrao- Sial, Raquel Blazquez, Ivan Nuñez- Gil, Daniel Perez- Camargo, Javier Cobiella- Carnicer, Juan Miguel Miranda Torron, Maria Alejandra Giraldo, Luis Maroto Castellanos   +9 more
doaj   +3 more sources

Modified Del Nido Versus Custodiol® Cardioplegia for Myocardial Protection in Adult Patients Undergoing Cardiac Surgery; A Prospective Randomized Double-Blinded Clinical Trial [PDF]

Annals of Cardiac Anaesthesia
Background: Cardioplegia is essential for myocardial protection. Modified Del Nido and Custodiol® cardioplegia have been successfully used; however, a limited number of clinical trials compared both solutions.
Mahdy A. Abdelhady, Abeer S. Goda, Mohamed S. Sayed Gomaa, Mohamed A. Hamed, Alyaa A. S. Mohammed Hassan   +4 more
doaj   +3 more sources

Custodiol versus Blood Cardioplegia: Comparison of Myocardial Immunohistochemical Analysis and Clinical Outcomes [PDF]

Brazilian Journal of Cardiovascular Surgery, 2022
Introduction: Custodiol (histidine-tryptophan-ketoglutarate) and repetitive blood cardioplegia are the solutions for myocardial protection and cardiac arrest. In this study, we aimed to compare immunohistochemical analysis, clinical outcomes, and cardiac
Onur Sen, Unal Aydin, Ersin Kadirogullari, Salih Güler, Süheyla Gonca, Seyhun Solakoğlu, Mehmet Karaçalılar, Barış Timur, Burak Onan   +8 more
doaj   +3 more sources

Protección miocárdica mediante cardioplejia Custodiol® frente a cristaloide convencional en cirugía cardíaca compleja. Resultados de una serie institucional

Cirugia Cardiovascular, 2021
Resumen: Introducción: La cardioplejia Custodiol® ofrece protección miocárdica durante tres horas mediante dosis única permitiendo realizar procedimientos complejos sin interrupción.
Laura Varela Barca
exaly   +3 more sources

Evaluating a Novel Cell-Free Preservation Solution for Human Cardiomyocyte Protection: A Proof-of-Concept Study. [PDF]

Biomed Res Int
Background Heart transplantation remains the definitive therapy for end‐stage heart failure; however, its clinical impact is constrained by donor availability and preservation‐associated injury. Static cold storage (SCS) with cardioplegic solutions such as Custodiol is the current clinical standard of care, yet extended cold ischemia markedly increases
Beckers C, Kraemer S, Theißen A, Kunze M, Soppert J, Schurgers L, Veltrop R, Doorschodt B, Tolba RH, Larmann J, Bleilevens C.   +10 more
europepmc   +2 more sources

Cardioplegia Strategies in Minimally Invasive Aortic Valve Replacement: An Inverse Probability of Treatment Weighting Analysis [PDF]

Medicina
Background and Objectives: Optimal myocardial protection during minimally invasive aortic valve replacement (MIAVR) is debated. We compared four cardioplegia strategies.
Lukman Amanov, Sadeq Ali-Hasan-Al-Saegh, Arian Arjomandi Rad, Antonia Annegret Jauken, Prokopis-Andreas Zotos, Jawad Salman, Thanos Athanasiou, Ezin Deniz, Stefan Ruemke, Bastian Schmack, Arjang Ruhparwar, Alina Zubarevich, Alexander Weymann   +12 more
doaj   +2 more sources

Myocardial protection during surgery for infective endocarditis: retrospective, single center, risk-adjusted study [PDF]

Journal of Cardiothoracic Surgery
Objectives Current evidence does not support superiority of one cardioplegia type over another, but stems from low-risk populations. Therefore, we compared outcomes of multimorbid, high-risk infective endocarditis (IE) patients receiving Custodiol ...
Murat Mukharyamov, Tulio Caldonazo, Philine Fleckenstein, Sebastian Freiburger, Hristo Kirov, Mathias Pletz, Stefan Hagel, Jürgen Bogoviku, Sandesh Dinesh, Stefan Glöckner, Micha Banz, Mahmoud Diab, Torsten Doenst, the IKARUS study group   +13 more
doaj   +2 more sources

A Systematic Review of Renal Perfusion in Complex Abdominal Aortic Aneurysm Open Repair [PDF]

Journal of Cardiovascular Development and Disease
Introduction: This systematic review aims to analyze the current literature regarding 30-day mortality and postoperative acute kidney disease (AKI) in complex abdominal aortic aneurysms (cAAAs), which included juxtarenal aortic aneurysm (JAA), suprarenal
Diletta Loschi, Enrico Rinaldi, Annarita Santoro, Nicola Favia, Nicola Galati, Germano Melissano   +5 more
doaj   +2 more sources

Lecithin‐Modified Nanoscale Oxygen Carriers (LENOX): New Designed Perfluorocarbon‐Based Artificial Oxygen Carriers Ready‐to‐Use in Clinically Relevant Media

Advanced NanoBiomed Research
Perfluorocarbons (PFCs) have been part of artificial oxygen carrier (AOC) research for decades. PFC‐based AOCs stand out because of their characteristic physicochemical properties such as high gas solubility, low viscosity, high vapor pressure, and their
Fabian Nocke, Martin A. Schroer, Marina Penzel, Miriam Cantore, Andrea U. Steinbicker, Katja B. Ferenz   +5 more
doaj   +2 more sources

How different cardioplegic solutions influence genes expression and cytokine response in an immature rat heart model of ischemia/reperfusion? [PDF]

PLoS ONE
IntroductionThe use of cardioplegia not only achieves cardiac arrest but also minimizes ischemic/reperfusion (I/R) injury, potentially improving short- or long-term outcomes.
Arslan Mamedov, Dovydas Gečys, Povilas Jakuška, Rimantas Treinys, Deimantė Narauskaitė, Serik Aitaliyev, Eglė Rumbinaitė, Dainius Karčiauskas, Rimantas Benetis, Edgaras Stankevičius   +9 more
doaj   +2 more sources