Results 41 to 50 of about 1,586 (155)

TECHNIQUE OF EXTRACORPOREAL PARTIAL NEPHRECTOMY IN TERMS OF PHARMACO-COLD ISCHEMIA WITHOUT CROSSING THE URETER WITH RENAL VESSELS ORTHOTOPIC REPLANTATION IN PATIENTS WITH RENAL CELL CARCINOMA

Вестник урологии, 2015
Background. The most difficult is to determine medical tactics in patients with renal cell carcinoma (RCC) with intraparenchimal and central localization in the single, the only functioning kidney, as well as with a combination of tumor and other ...
Alexander Gritskevitch, S. Il'in, Irina Timina, Andrey Zotikov, Grigoriy Karmazanovskiy, Alexander Teplov, A. Pokrovskiy, V. Kubyshkin   +7 more
doaj   +1 more source

Custodiol® supplemented with synthetic human relaxin decreases ischemia-reperfusion injury after porcine kidney transplantation / [PDF]

, 2021
Objective. Ischemia-reperfusion injury (IRI) is inevitable after kidney transplantation (KT), impairing outcomes. Relaxin-2 (RLX) is a promising insulin-related peptide hormone that protects against renal IRI in rodents, although large animal models are ...
Baušys, Augustinas,, Bettina Leber, Juste Maneikyte, Maneikytė, Justė,, Dschietzig, Thomas Bernd,, Schemmer, Peter,, Feldbacher, Nicole,, Augustinas Bausys, Leber, Bettina,, Peter Schemmer, Philipp Stiegler, Kestutis Strupas, Strupas, Kęstutis,, Nicole Feldbacher, Thomas Dschietzig, Jennifer Weber, Weber, Jennifer,, Stiegler, Philipp,   +17 more
core   +1 more source

Monitoring Mitochondrial Function With High‐Resolution Respirometry During Ex‐Situ Heart Perfusion

Artificial Organs, EarlyView.
Normothermic ESHP preserves mitochondrial respiratory function over 6 h in a porcine model (n = 6): OXPHOS capacities across NADH‐, fatty‐acid‐, and succinate‐linked pathways remain stable, with reduced cytochrome‐c control efficiency indicating improved outer‐membrane integrity. HRR provides a rapid, actionable readout for organ assessment.
Lukas Stastny, Julia Hofmann, Andras T. Meszaros, Alexandra Ampferer, Gabriel Putzer, Nina Perkins, Natalie Huemer, Florian Sommerauer, Judith Martini, Julian Wagner, Michael Grimm, Stefan Schneeberger, Julia Dumfarth   +12 more
wiley   +1 more source

Evaluation of Liver Grafts During Machine Perfusion at 20°C via Metabolization of 13C‐Methacetin

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Evaluative measures, helping to decide whether marginal grafts can be used for transplantation or rather be discarded are of utmost importance but yet basically underdeveloped. Livers of varying quality were subjected to machine perfusion at 20°C for 2 h.
Charlotte von Horn, Laura Malkus, Derya Berger, Stefanie Bertram, Thomas Minor   +4 more
wiley   +1 more source

Custodiol® HTK Cardioplegia Use in Robotic Mitral Valve

, 2013
Robotic surgery is a growing subspecialty in cardiac surgery. Custodiol® HTK cardioplegia offers long-term myocardial protection, decreased metabolism, and eliminates multiple cardioplegia dosing.
Ed DeLaney, Gerard Turi, Thomas Stapleton, Nirav Patel   +3 more
core   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, Volume 604, Issue 16, Page 6792-6816, 15 August 2026.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

Investigating the Impact of Carboxylated Polystyrene Nanoplastics in the Liver Using Cell Lines and Precision‐Cut Liver Slices

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Increasing reports of plastic accumulation in human tissue have raised concerns about potential adverse health outcomes. Evidence of negative effects of nanoplastics is heterogeneous and provides limited insights into the underlying pathogenic toxicity mechanisms in humans. Methods In the present study, carboxylate‐modified
Namrata Pandey, Paula Boeira, Nathaniel J. Clark, Eleanor T. Walker, Somaiah Aroori, Jemimah Denson, Richard C. Thompson, Matthew E. Cramp, Shilpa Chokshi, Ashwin Dhanda   +9 more
wiley   +1 more source

The impact of pericardial approach and myocardial protection onto postoperative right ventricle function reduction

Journal of Cardiothoracic Surgery, 2018
Background The reduction of RV function after cardiac surgery is a well-known phenomenon. It could persist up-to one year after the operation and often leads to an incomplete recovery at follow-up echocardiographic control.
Marco Zanobini, Claudia Loardi, Paolo Poggio, Gloria Tamborini, Fabrizio Veglia, Alessandro Di Minno, Veronika Myasoedova, Liborio Francesco Mammana, Raoul Biondi, Mauro Pepi, Francesco Alamanni, Matteo Saccocci   +11 more
doaj   +1 more source

Custodiol versus blood cardioplegia in pediatric cardiac surgery: a randomized controlled trial

European Journal of Medical Research, 2023
Background Blood-based cardioplegia is the standard myocardial protection strategy in pediatric cardiac surgery. Custadiol (histidine-tryptophan-ketoglutarate), an alternative, may have some advantages but is potentially less effective at myocardial ...
Ahmed F. Elmahrouk, Mohammad S. Shihata, Osman O. AL-Radi, Amr A. Arafat, Musleh Altowaity, Bayan A. Alshaikh, Mohamed N. Galal, Abdulbadee A. Bogis, Haneen Y. Al Omar, Wesal J. Assiri, Ahmed A. Jamjoom   +10 more
doaj   +1 more source

Multimodal Assessment of Kidney Quality During 24‐h of Normothermic Machine Perfusion

Artificial Organs, Volume 50, Issue 6, Page 851-865, June 2026.
Normothermic machine perfusion (NMP) has emerged as a promising tool for assessing kidney quality prior to transplantation; however, reliable biomarkers remain to be established. In this study, thirteen porcine kidneys were perfused for 24 h using an autologous leukocyte‐filtered whole blood‐based perfusate applying urine recirculation.
Marlene Pühringer, Magdalena Kött, Andras T. Meszaros, Michael J. Blumer, Bettina Zelger, Stefan Redl, Martin Hermann, Thomas Resch, Simon Mathis, Gabriel Putzer, Judith Martini, Christina Bogensperger, Franka Messner, Julia Hofmann, Margot Fodor, Andrea Griesmacher, Annemarie Weissenbacher, Theresa Hautz, Gert Mayer, Hannes Neuwirt, Gerald Brandacher, Silvia Oberparleiter, Stefan Schneeberger   +22 more
wiley   +1 more source