Results 201 to 210 of about 1,870,108 (304)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Proof of Concept for Metacarpal Reconstruction Using a Custom 3-dimensional-Printed Titanium Implant: Design, Manufacturing, Surgical Technique, and Early Postoperative Outcomes. [PDF]

J Hand Surg Glob Online
Wesorick B, Oke O, Withrow NE, Herrera D, Mann T, Lewis L, Nurbhai N.   +6 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A Prospective Study on Longevity of Different Post and Core Systems in Endodontically Treated Teeth.

J Pharm Bioallied Sci
Patil S, Vidyasagar BS, Priya P, Dhumal AA, Thakkar J, Dave M.   +5 more
europepmc   +1 more source

Low-Cost DLW Setup for Fabrication of Photonics-Integrated Circuits. [PDF]

Micromachines (Basel)
Moreira A, Fantoni A, Fernandes M, Fidalgo J.   +3 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Single-stage craniectomy and custom titanium cranioplasty for intradiploic arachnoid cyst: illustrative case. [PDF]

J Neurosurg Case Lessons
Siversson S, Foo S, Morrison DA, Honeybul S.   +3 more
europepmc   +1 more source

Custom and Its Revival in Transnational Private Law [PDF]

, 2008
Dalhuisen, J. H.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Development and Characterization of a Tunable PDMS Substrate Model for Investigating Elastic Properties and Mechanical Stretching in Intervertebral Disc Cells. [PDF]

JOR Spine
Hasler J, Lamoca M, Schimmelpfennig K, Zhang S, Hitzl W, Farajollahi S, Abhyankar VV, Lewis CL, Liu R, Wuertz-Kozak K.   +9 more
europepmc   +1 more source