Custom Antibiotic-Coated Intramedullary Nails for Infected Tibial and Femoral Nonunions: Retrospective Cohort Study and Surgical Technique. [PDF]
Chow VJ, Mannambeth R.
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Comparing the Effectiveness of Different Types of Orthoses in Preventing Diabetic Foot Ulcer Recurrence: A Systematic Review of Randomized Clinical Trials. [PDF]
Amini B +2 more
europepmc +1 more source
Aldila Krisnaresanti +2 more
openaire +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Sequential Bilateral Cochlear Implantation via the Transmastoid Labyrinthotomy Approach Using Custom-Made Electrodes in a Pediatric Patient With Common Cavity Deformities: A Case Report. [PDF]
Vigliaroli CL +7 more
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Custom-Made Compression Elastic Garments for Vascular Anomalies and Edematous Disorders: Objective and Subjective Outcomes in a Multi-Institutional Clinical Series. [PDF]
Akita S +5 more
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

