Results 231 to 240 of about 1,258,966 (356)

A risk-based framework to guide oversight of nucleic acid constructs. [PDF]

Front Bioeng Biotechnol
Cerles A, Dingus-Simmons A, Casagrande R.   +2 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Hydroxypropyl Cellulose as an Effective Binder for Low-Temperature Screen-Printed Porous Carbon Counter Electrodes for Indoor Dye-Sensitized Solar Cells. [PDF]

Nanomaterials (Basel)
Speranza R, Morale E, Sergiacomi F, Bisceglie A, Mogli G, Martellone S, Lamberti A.   +6 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Custom-made foot orthoses for the treatment of foot pain

Background: Custom foot orthoses are commonly recommended for the treatment of foot pain. Objectives: To evaluate the effectiveness of custom foot orthoses for different types of foot pain.
Joshua Burns (6314219), Verona du Toit (21331445), Joel A. Radford (21331442), Fiona Hawke (21132764)   +3 more
core  

Technical Feasibility of Custom-Fabricated Auxetic Foam Insoles for Plantar Pressure Redistribution: An Exploratory Pilot and Bootstrap Resampling Investigation. [PDF]

Materials (Basel)
Batey L, Jackson EM, Zeng C, Pillay S.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Custom-Made Monoflange Acetabular Component for Revision Hip Arthroplasty in Paprosky Type IIIA Defect: A Case Report. [PDF]

J Orthop Case Rep
Boobathi RRS, Saravanan M, Loganathan B.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Osseointegrated Dental Implants as Retention Systems for Digit Prostheses in Finger Amputations. [PDF]

Adv Orthop
Alzoubi A, Alhiasat I, Almigdad A, Rababah A, Al-Khawaldeh A.   +4 more
europepmc   +1 more source