Results 61 to 70 of about 14,356 (250)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Analysis of modern air transportation in Russia
Modern air cargo transport is an important part of global logistics and trade. They provide fast and efficient delivery of goods all over the world. In recent years, there have been several significant changes in the development of air routes both in the
T. A. Petrova, V. A. Kardanov
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Aim: The Southeast European Law Enforcement Center (hereinafter: SELEC) is a centre for criminal cooperation between police forces and customs services of the Balkan and other neighbouring countries, including Hungary, primarily for the prevention and ...
Barna Szabó
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
While economic development brings serious environmental problems, technological advances can effectively reduce pollution, which helps to achieve the Sustainable Development Goals.
Yuling Ruan, Anqi Zhang
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Pricing Strategy and Blockchain-Enabled Data Sharing in Cross-Border Port Systems
The study examines the impact of pricing strategies on the competition and cooperation of cross-border ports, focusing on unified pricing and differential pricing.
Huida Zhao, Chanjuan Liu
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Water resource forecasting with machine learning and deep learning: A scientometric analysis
Water prediction plays a crucial role in modern-day water resource management, encompassing both hydrological patterns and demand forecasts. To gain insights into its current focus, status, and emerging themes, this study analyzed 876 articles published ...
Chanjuan Liu +4 more
doaj +1 more source

