Results 61 to 70 of about 15,623 (252)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Public low-carbon related characteristics and their (dis)approval of nuclear energy in China against the backdrop of climate change: an analysis of influence mechanism

Frontiers in Environmental Science
Developing nuclear energy is a controversial issue despite its inherently low-carbon emissions life cycle. Considering low-carbon awareness, perception of barriers and low-carbon behaviors as important personal characteristics in the context of climate ...
Hongyan Su, Xiaodan Guo, Jing Wang
doaj   +1 more source

Features of customs revenue administration in the Eurasian Economic Union

RUDN Journal of Economics, 2017
In the article, on the basis of the analysis of the administration of customs revenues in the Russian Federation, the Republic of Belarus, the Republic of Kazakhstan, the Republic of Kyrgyzstan, the Republic of Armenia, general features of the mechanism ...
G I Nemirova
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Analysis of modern air transportation in Russia

Вестник университета
Modern air cargo transport is an important part of global logistics and trade. They provide fast and efficient delivery of goods all over the world. In recent years, there have been several significant changes in the development of air routes both in the
T. A. Petrova, V. A. Kardanov
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The opportunities for criminal cooperation between the investigative authority of the National Tax and Customs Administration and the Southeast European Law Enforcement Center based on working experiences and best practices

Belügyi Szemle
Aim: The Southeast European Law Enforcement Center (hereinafter: SELEC) is a centre for criminal cooperation between police forces and customs services of the Balkan and other neighbouring countries, including Hungary, primarily for the prevention and ...
Barna Szabó
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The spatial spillover effect of green technology innovation on water pollution–evidence from 283 Chinese cities

Frontiers in Environmental Economics
While economic development brings serious environmental problems, technological advances can effectively reduce pollution, which helps to achieve the Sustainable Development Goals.
Yuling Ruan, Anqi Zhang
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source