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Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source

Actions to respond to a troubled immigration environment. [PDF]

Front Public Health
Galletly C, Ruelas D.
europepmc +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source

Misguided tariffs will not solve the United States' overdose crisis. [PDF]

Lancet Reg Health Am
Karamouzian M, Werb D.
europepmc +1 more source

Public value management in rural China through digital engagement, identity recognition and moral legitimacy. [PDF]

Sci Rep
Liu Z, Han Z.
europepmc +1 more source

Analysis of COVID-19 vaccination experience of the Los Pastos, Wounaan, and Misak Misak indigenous peoples from Bogotá, Colombia. [PDF]