Results 161 to 170 of about 289,961 (295)

Communication from the Commission on steel policy. Proposal for a Council Decision on a contribution from the general budget of the Communities to the ECSC to finance social measures connected with the restructuring of the steel industry. COM (88) 343 final, 16 June 1988 [PDF]

, 1988

core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The policies of the democratic government of India on the management of rare diseases. [PDF]

J Family Med Prim Care
Shamim T.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Reconsideration of Secure Communities rollout reveals preemptive local-federal cooperation in immigration enforcement. [PDF]

Proc Natl Acad Sci U S A
Nunez CDV, Bhatt S, Seif BF, Mendoza FS, Laitin DD, Asad AL.   +5 more
europepmc   +1 more source

Збірник текстів і завдань з дисципліни «Іноземна мова (за професійним спрямуванням)» (англійська мова) для організації самостійної роботи студентів 2 курсу денної форми навчання напряму підготовки 6.070101 «Транспортні технології» (за видами транспорту). [PDF]

, 2012
Шумейко, Л.В.
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Gender identity's impact on Pakistan's adoption of emotion-focused, and religious-spiritual coping mechanisms during the COVID-19 pandemic. [PDF]

Discov Ment Health
Latif MA.
europepmc   +1 more source

Hearing to Examine Warrantless Smartphone Searches at the Border: Hearing Before the Subcomm. on Fed. Spending Oversight & Emergency Mgmt. of the S. Comm. on Homeland Sec. & Governmental Affairs, 115th Cong., July 11, 2018 (Statement of Laura K. Donohue) [PDF]

, 2018
Donohue, Laura K
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source