Results 121 to 130 of about 388,688 (309)

TAJIKISTAN - CUSTOMS: OPPORTUNITIES AND PROSPECTS OF INTERACTION

Проблемы постсоветского пространства, 2017
Article is devoted to the integration choice of the Republic of Tajikistan and the prospects for cooperation with the Customs Union and the Eurasian Economic Union.
Z. A. Dadabaeva
doaj  

The economics of customs unions in the Commonwealth of Independent States [PDF]

In the aftermath of the breakup of the Soviet Union, trade among the new independent states collapsed. To help reestablish interstate trade, the 12 members of the Commonwealth of independent States (CIS) established a Free Trade Area. More recently, four
Michalopoulos, Constantine, Tarr, David
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

GOODS IN THE EUROPEAN UNION – THE MAIN CHARACTERISTIC OF THE EUROPEAN UNION, WITH SPECIAL EMPHASIS ON CUSTOMS UNION

Pravo, 2009
Everything that a current business world is involving around, is getting more incomes. Custum union is the best example which is confirming that business interest is more than often of great influence on politics and on political leaders.
Predrag Mirković, Vladimir Đurić
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

THE QUESTION ABOUT SOCIAL ORGANIZATION OF KAZAKHSTANI BUSINESS UNDER CONDITIONS OF CUSTOMS UNION AND COMMON FREE MARKET ZONE

Хабаршы. Психология және социология сериясы, 2015
Creation of two integrating mechanisms: Customs Union and Com­ mon Free Market Zone favors forming fundamental conditions for accel­ erated transferring of three countries: Russia, Kazakhstan and Belarus to neoindustrial progress stage.
Zh. A. Nurbekova, Z. Zh. Zhanazarova, A. Beisenova   +2 more
doaj   +2 more sources

Logistic model of import of goods into the territory of the customs Union of Belarus, Kazakhstan and the Russian Federation

Путеводитель предпринимателя, 2020
The article deals with the application of the tools of network models for the organization of processes in the movement of goods across the customs border of the Customs Union.
S. S. Ilyukhina
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source