Results 91 to 100 of about 801,697 (279)
Gap structure of 1D cut and project Hamiltonians
We study the gap properties of nearest neighbors tight binding models on quasiperiodic chains. We argue that two kind of gaps should be distinguished: stable and transient. We show that stable gaps have a well defined quasiperiodic limit. We also show that there is a direct relation between the gap size and the gap label.
Jagannathan, Anuradha +2 more
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Branch and Cut Method in the PLATO-N Project
We present the multiple load structural topology design problems with discrete design variables which are considered in the PLATO-N project. For the considered class of problems a global optimization method based on the concept of branch and cut is ...
Canh, Nam Nguyen +5 more
core
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The optimization of parameters for the construction of cut off walls using high spray method plays a crucial role in improving the permeability stability of hydraulic structures and ensuring the safe operation of water conservancy projects.
Da Liu +6 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Groundwater impact of open cut coal mine and an assessment methodology: A case study in NSW
Large scale open cut coal mining operations have significant impacts to groundwater in surrounding areas in both active and post-mining phases. The prediction of water inflows into a surface mine excavation is one of the many components involved in mine ...
Liang Zhao, Ting Ren, Ningbo Wang
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

