Results 91 to 100 of about 801,697 (279)

Gap structure of 1D cut and project Hamiltonians

open access: yesJournal of Physics: Conference Series, 2017
We study the gap properties of nearest neighbors tight binding models on quasiperiodic chains. We argue that two kind of gaps should be distinguished: stable and transient. We show that stable gaps have a well defined quasiperiodic limit. We also show that there is a direct relation between the gap size and the gap label.
Jagannathan, Anuradha   +2 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Branch and Cut Method in the PLATO-N Project

open access: yes, 2008
We present the multiple load structural topology design problems with discrete design variables which are considered in the PLATO-N project. For the considered class of problems a global optimization method based on the concept of branch and cut is ...
Canh, Nam Nguyen   +5 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Numerical simulation study on the construction of cut off walls using high-pressure jet grouting based on SPH method

open access: yesFrontiers in Earth Science
The optimization of parameters for the construction of cut off walls using high spray method plays a crucial role in improving the permeability stability of hydraulic structures and ensuring the safe operation of water conservancy projects.
Da Liu   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Groundwater impact of open cut coal mine and an assessment methodology: A case study in NSW

open access: yesInternational Journal of Mining Science and Technology, 2017
Large scale open cut coal mining operations have significant impacts to groundwater in surrounding areas in both active and post-mining phases. The prediction of water inflows into a surface mine excavation is one of the many components involved in mine ...
Liang Zhao, Ting Ren, Ningbo Wang
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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