Results 121 to 130 of about 688,997 (292)

Pengendalian Waktu Proyek dengan Menggunakan Metode Critical Chain Project Management (Ccpm) (Studi Kasus: Pembangunan Jalan SMK IT Payakumbuh)

open access: yesJurnal Teknik Industri: Jurnal Hasil Penelitian dan Karya Ilmiah dalam Bidang Teknik Industri, 2016
Penelitian ini dilakukan untuk membuat perencanaan proyek jalan SMK IT Payakumbuh yang diharapkan tidak seperti proyek sebelumnya, dimana terjadi ketidaksesuaian antara perencanaan dan pelaksanaannya.
Suherman Suherman
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Self-Matching Properties of Beatty Sequences [PDF]

open access: yes, 2006
We study the selfmatching properties of Beatty sequences, in particular of the graph of the function $\lfloor j\beta\rfloor $ against $j$ for every quadratic unit $\beta\in(0,1)$.
Masáková, Zuzana, Pelantová, Edita
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Periodic diffraction patterns for 1D quasicrystals

open access: yes, 2005
A simple model of 1D structure based on a Fibonacci sequence with variable atomic spacings is proposed. The model allows for observation of the continuous transition between periodic and non-periodic diffraction patterns.
Buczek, Pawel   +2 more
core   +1 more source

Construction procedures for ultra-large twin foundation pits in metro stations

open access: yesShenzhen Daxue xuebao. Ligong ban
The Shenzhen Dayun Transportation Hub project includes both the main station foundation pit and the transportation core foundation pit, which are closely adjacent and excavated simultaneously. This configuration poses significant construction challenges
FEI Jianbo   +3 more
doaj   +1 more source

Assessment of Adoption Status of Management Practices for West African Dwarf Goat Production in Southwestern Nigeria [PDF]

open access: yesTropicultura, 2006
This study was conducted in the Obafemi Awolowo University Rural Development Project communities in Southwestern Nigeria to investigate the adoption status of West African Dwarf Goat (WADG) management practices among the seventy (70) project participants
Odeyinka, SM., Torimiro, DO.
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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