Results 151 to 160 of about 801,697 (279)
Climate-Impact Uncertainty in Bio-Asphalt-Rubber Binders: Probabilistic Cradle-to-Gate Screening of Bio-Oil Inventory and Crumb Rubber Allocation. [PDF]
Zhang Y, Zhao X.
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Development and Content Validation of Entrustable Professional Activities for Community Pharmacy Practice Experiences in Brazil. [PDF]
de Almeida Romani LF, Lima MG.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
A novel integrated injection snare for single-device endoscopic mucosal resection. [PDF]
Rao X +6 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Study on the failure mechanism and cutting efficiency of rebar in linear cutting based on the finite-discrete element method. [PDF]
Yi X, Wei Y, Chen J, Wang T.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity. [PDF]
Slovackova J +11 more
europepmc +1 more source

