Results 71 to 80 of about 658,878 (281)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On intuitionistic branching tense logic with weak induction
Lietuvos Matematikos Rinkinys, 1998 In the paper, the first-order branching tense logic calculus is given: LB J with the weak induction, that is to say with the axiom (A ∧ A O ☐ A) ⊃ ☐ A instead of the induction axiom (A ∧ ☐ (A ⊃ O A)) ⊃ ☐ A.
Romas Alonderis
doaj +3 more sources
Taylor expansion in linear logic is invertible [PDF]
Logical Methods in Computer Science, 2018 Each Multiplicative Exponential Linear Logic (MELL) proof-net can be expanded into a differential net, which is its Taylor expansion. We prove that two different MELL proof-nets have two different Taylor expansions.
Daniel de Carvalho
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Cut-elimination and Normalization Theorems for Connexive Logics over Wansing’s C
Bulletin of the Section of LogicGentzen-style sequent calculi and Gentzen-style natural deduction systems are introduced for a family (C-family) of connexive logics over Wansing’s basic constructive connexive logic C.
Norihiro Kamide
doaj +1 more source
Elimination of Cucumber mosaic virus from gladiolus by meristem tip culture, thermotherapy and electrotherapy [PDF]
مجله بیوتکنولوژی کشاورزی, 2016 Flowers of Gladiolus sp. are among the top six flowers of export value and in Iran take the second place in the production of cut flowers. Cucumber mosaic virus is one of the most common viruses in gladiolus worldwide.
Sorraya Tourang +2 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
On the Herbrand content of LK [PDF]
Electronic Proceedings in Theoretical Computer Science, 2016 We present a structural representation of the Herbrand content of LK-proofs with cuts of complexity prenex Sigma-2/Pi-2. The representation takes the form of a typed non-deterministic tree grammar of order 2 which generates a finite language of first ...
Bahareh Afshari +2 more
doaj +1 more source
The failure of cut-elimination in cyclic proof for first-order logic with inductive definitions [PDF]
, 2021 Yukihiro Oda +2 more
openalex +1 more source