Results 81 to 90 of about 2,879,484 (330)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Elimination of Cucumber mosaic virus from gladiolus by meristem tip culture, thermotherapy and electrotherapy [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2016
Flowers of Gladiolus sp. are among the top six flowers of export value and in Iran take the second place in the production of cut flowers. Cucumber mosaic virus is one of the most common viruses in gladiolus worldwide.
Sorraya Tourang   +2 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

On the Herbrand content of LK [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2016
We present a structural representation of the Herbrand content of LK-proofs with cuts of complexity prenex Sigma-2/Pi-2. The representation takes the form of a typed non-deterministic tree grammar of order 2 which generates a finite language of first ...
Bahareh Afshari   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Multiplicative-Additive Proof Equivalence is Logspace-complete, via Binary Decision Trees [PDF]

open access: yesLogical Methods in Computer Science, 2017
Given a logic presented in a sequent calculus, a natural question is that of equivalence of proofs: to determine whether two given proofs are equated by any denotational semantics, ie any categorical interpretation of the logic compatible with its cut ...
Marc Bagnol
doaj   +1 more source

Reasoning about Unreliable Actions [PDF]

open access: yes, 2012
We analyse the philosopher Davidson's semantics of actions, using a strongly typed logic with contexts given by sets of partial equations between the outcomes of actions.
White, Graham
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Modified Anderson-Darling Test-Based Target Detector in Non-Homogenous Environments

open access: yesSensors, 2014
A constant false alarm rate (CFAR) target detector in non-homogenous backgrounds is proposed. Based on K-sample Anderson-Darling (AD) tests, the method re-arranges the reference cells by merging homogenous sub-blocks surrounding the cell under test (CUT)
Yang Li   +3 more
doaj   +1 more source

On Constructive Connectives and Systems [PDF]

open access: yesLogical Methods in Computer Science, 2010
Canonical inference rules and canonical systems are defined in the framework of non-strict single-conclusion sequent systems, in which the succeedents of sequents can be empty.
Arnon Avron, Ori Lahav
doaj   +1 more source

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