Results 61 to 70 of about 117,954 (285)
On the non-confluence of cut-elimination
The Journal of Symbolic Logic, 2011 AbstractWe study cut-elimination in first-order classical logic. We construct a sequence of polynomial-length proofs having a non-elementary number of different cut-free normal forms. These normal forms are different in a strong sense: they not only represent different Herbrand-disjunctions but also differ in their prepositional structure.This result ...
Matthias Baaz, Stefan Hetzl
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Modular cut-elimination: Finding proofs or counterexamples
, 2006 . Modular cut-elimination is a particular notion of ”cut-elimination in the presence of non-logical axioms ” that is preserved under the addition of suitable rules.
Ciabattoni, Agata +3 more
core +1 more source
Logical Methods in Computer Science, 2017 We propose new sequent calculus systems for orthologic (also known as minimal quantum logic) which satisfy the cut elimination property. The first one is a simple system relying on the involutive status of negation. The second one incorporates the notion
Olivier Laurent
doaj +1 more source
On the elimination of quantifier-free cuts
Theoretical Computer Science, 2011 When investigating the complexity of cut-elimination in first-order logic, a natural subproblem is the elimination of quantifier-free cuts. So far, the problem has only been considered in the context of general cut-elimination, and the upper bounds that have been obtained are essentially double exponential. In this note, we observe that a method due to
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On intuitionistic branching tense logic with weak induction
Lietuvos Matematikos Rinkinys, 1998 In the paper, the first-order branching tense logic calculus is given: LB J with the weak induction, that is to say with the axiom (A ∧ A O ☐ A) ⊃ ☐ A instead of the induction axiom (A ∧ ☐ (A ⊃ O A)) ⊃ ☐ A.
Romas Alonderis
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Taylor expansion in linear logic is invertible [PDF]
Logical Methods in Computer Science, 2018 Each Multiplicative Exponential Linear Logic (MELL) proof-net can be expanded into a differential net, which is its Taylor expansion. We prove that two different MELL proof-nets have two different Taylor expansions.
Daniel de Carvalho
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source