Results 81 to 90 of about 118,600 (325)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A simple proof that super consistency implies cut elimination [PDF]
International audienceWe give a simple and direct proof that super-consistency implies the cut elimination property in deduction modulo. This proof can be seen as a simpli cation of the proof that super-consistency implies proof normalization.
Dowek, Gilles +3 more
core +1 more source
On the Herbrand content of LK [PDF]
We present a structural representation of the Herbrand content of LK-proofs with cuts of complexity prenex Sigma-2/Pi-2. The representation takes the form of a typed non-deterministic tree grammar of order 2 which generates a finite language of first ...
Bahareh Afshari +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
A Simple Proof That Super-Consistency Implies Cut Elimination [PDF]
We give a simple and direct proof that super-consistency implies the cut elimination property in deduction modulo. This proof can be seen as a simplification of the proof that super-consistency implies proof normalization.
Dowek, Gilles, Hermant, Olivier
core +1 more source
The purpose of this study was to examine changes to the budgets of women’s athletics, men’s basketball, and football when an NCAA Division I intercollegiate men’s team was eliminated. Stakeholder theory provided the theoretical framework for the study.
Anne Marx, Joel Cormier, Roman Ciapalo
doaj
Modified Anderson-Darling Test-Based Target Detector in Non-Homogenous Environments
A constant false alarm rate (CFAR) target detector in non-homogenous backgrounds is proposed. Based on K-sample Anderson-Darling (AD) tests, the method re-arranges the reference cells by merging homogenous sub-blocks surrounding the cell under test (CUT)
Yang Li +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Algebraic proofs of cut elimination [PDF]
Algebraic proofs of the cut-elimination theorems for classical and intuitionistic logic are presented, and are used to show how one can sometimes extract a constructive proof and an algorithm from a proof that is nonconstructive.
Jeremy Avigad
core

