Results 81 to 90 of about 117,954 (285)

The Financial Impact of Eliminating a NCAA Division I Men’s Sport on the Athletic Budget: Is Title IX to Blame?

open access: yesJournal of Intercollegiate Sport, 2023
The purpose of this study was to examine changes to the budgets of women’s athletics, men’s basketball, and football when an NCAA Division I intercollegiate men’s team was eliminated.  Stakeholder theory provided the theoretical framework for the study. 
Anne Marx, Joel Cormier, Roman Ciapalo
doaj  

Multiplicative-Additive Proof Equivalence is Logspace-complete, via Binary Decision Trees [PDF]

open access: yesLogical Methods in Computer Science, 2017
Given a logic presented in a sequent calculus, a natural question is that of equivalence of proofs: to determine whether two given proofs are equated by any denotational semantics, ie any categorical interpretation of the logic compatible with its cut ...
Marc Bagnol
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

On Constructive Connectives and Systems [PDF]

open access: yesLogical Methods in Computer Science, 2010
Canonical inference rules and canonical systems are defined in the framework of non-strict single-conclusion sequent systems, in which the succeedents of sequents can be empty.
Arnon Avron, Ori Lahav
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Valentini's cut-elimination for provability logic resolved

open access: yes, 2015
Valentini (1983) has presented a proof of cut-elimination for provability logic GL for a sequent calculus using sequents built from sets as opposed to multisets, thus avoiding an explicit contraction rule.
Ramanayake, Revantha, Gore, Rajeev
core   +1 more source

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