Results 51 to 60 of about 118,936 (260)

Cut elimination in coalgebraic logics

open access: yesInformation and Computation, 2010
We give two generic proofs for cut elimination in propositional modal logics, interpreted over coalgebras. We first investigate semantic coherence conditions between the axiomatisation of a particular logic and its coalgebraic semantics that guarantee that the cut-rule is admissible in the ensuing sequent calculus.
Dirk Pattinson, Lutz Schröder
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Focusing in Orthologic [PDF]

open access: yesLogical Methods in Computer Science, 2017
We propose new sequent calculus systems for orthologic (also known as minimal quantum logic) which satisfy the cut elimination property. The first one is a simple system relying on the involutive status of negation. The second one incorporates the notion
Olivier Laurent
doaj   +1 more source

On the non-confluence of cut-elimination

open access: yesThe Journal of Symbolic Logic, 2011
AbstractWe study cut-elimination in first-order classical logic. We construct a sequence of polynomial-length proofs having a non-elementary number of different cut-free normal forms. These normal forms are different in a strong sense: they not only represent different Herbrand-disjunctions but also differ in their prepositional structure.This result ...
Matthias Baaz, Stefan Hetzl
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On intuitionistic branching tense logic with weak induction

open access: yesLietuvos Matematikos Rinkinys, 1998
In the paper, the first-order branching tense logic calculus is given: LB J with the weak induction, that is to say with the axiom (A ∧ A O ☐ A) ⊃ ☐ A instead of the induction axiom (A ∧ ☐ (A ⊃ O A)) ⊃ ☐ A.
Romas Alonderis
doaj   +3 more sources

Taylor expansion in linear logic is invertible [PDF]

open access: yesLogical Methods in Computer Science, 2018
Each Multiplicative Exponential Linear Logic (MELL) proof-net can be expanded into a differential net, which is its Taylor expansion. We prove that two different MELL proof-nets have two different Taylor expansions.
Daniel de Carvalho
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Cut-elimination and Normalization Theorems for Connexive Logics over Wansing’s C

open access: yesBulletin of the Section of Logic
Gentzen-style sequent calculi and Gentzen-style natural deduction systems are introduced for a family (C-family) of connexive logics over Wansing’s basic constructive connexive logic C.
Norihiro Kamide
doaj   +1 more source

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