Results 111 to 120 of about 206,699 (375)

Dataset on Bi- and Multi-Nucleated Tumor Cells in Canine Cutaneous Mast Cell Tumors [PDF]

open access: yesarXiv, 2021
Tumor cells with two nuclei (binucleated cells, BiNC) or more nuclei (multinucleated cells, MuNC) indicate an increased amount of cellular genetic material which is thought to facilitate oncogenesis, tumor progression and treatment resistance. In canine cutaneous mast cell tumors (ccMCT), binucleation and multinucleation are parameters used in ...
arxiv  

ALKBH3‐Mediated M1A Demethylation of METTL3 Endows Pathological Fibrosis:Interplay Between M1A and M6A RNA Methylation

open access: yesAdvanced Science, EarlyView.
RNA modification is crucial in fibrosis diseases, but the role of m1A modification remains elusive. This study reveals that ALKBH3, an m1A demethylase, drives skin fibrosis by reshaping m6A RNA modification and stabilizing COL1A1 and FN1 mRNAs through METTL3, uncovering a crosstalk between m1A and m6A methylation in pathological events.
Liying Tu   +9 more
wiley   +1 more source

Immediate hypersensitivity reaction to carboxymethylcellulose in lidocaine jelly and dimethicone drops: A case report and mini‐review

open access: yesJournal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 217-221, December 2022., 2022
Carboxymethylcellulose (CMC, carmellose sodium) is an anionic water‐soluble polymer derived from native cellulose that is used as an excipient. Here, we report a case of urticaria caused by the CMC in lidocaine jelly and dimethicone drops. Abstract Excipient allergies are rare and difficult to diagnose.
Eri Hotta   +9 more
wiley   +1 more source

Toxic Epidermal Necrolyisis and Sepsis

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2016
A 63-year-old male patient suffered from myalgia, arthralgia cough and erythematous macules, with confluence to the thorax, limbs, thighs and the scrotum. The erythematous macules evolved to blisters with a positive Nikolsky’s sign.
Daniela Dias Alves   +4 more
doaj   +1 more source

A case of severe cutaneous adverse reaction following administration of the Janssen Ad26.COV2.S COVID-19 vaccine [PDF]

open access: gold, 2021
Kristen Lospinoso   +4 more
openalex   +1 more source

EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation

open access: yesAdvanced Science, EarlyView.
Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi   +12 more
wiley   +1 more source

Evaluation of sweating responses in patients with systemic connective tissue disorders using the quantitative sudomotor axon reflex test

open access: yesJournal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 208-216, December 2022., 2022
We investigated 85 patients on the relationship between the axon reflex sweat volume or the reaction time and Raynaud's phenomenon, skin symptoms and patient background. Most patients did not show a decrease in sweating, but one in three patients showed less sweating in summer than in winter.
Miwa Ashida   +5 more
wiley   +1 more source

NGF and therapeutic prospective: what have we learned from the NGF transgenic models?

open access: yesAnnali dell'Istituto Superiore di Sanità, 2015
It has been shown that topical nerve growth factor (NGF) administration induces healing action on human cutaneous, corneal and pressure ulcers, glaucoma, maculopathy and retinitis pigmentosa suggesting a therapeutic potential of NGF in human ...
Luigi Aloe, Maria Luisa Rocco
doaj   +1 more source

Single Channel Cutaneous Electrogastrography on Local White Rabbit (Oryctolagus cuniculus) and Its Electrogastrogram Classification Algorithm [PDF]

open access: yesarXiv, 2014
It has been a common practice to place electrodes based on external landmarks, rather than locating the appropriate organ first by imaging technuiqes such as CT scan, ultrasound, etc. Therefore, aside from abiding the cutaneous EGG (electrogastrography) electrodes placement rule, identification of its waveform should be performed to ease the validation
arxiv  

A case report of cutaneous mucormycosis of the hand after minor trauma in a patient with acute myeloid leukaemia [PDF]

open access: yes, 2019
Background: Mucormycosis is a rare but life-threatening infection, caused by fungi of the Mucorales order, which can be found in soil, rotting leaves or on animals. Through characteristic angioinvasive growth, infections with mucor spores can occur as a
Maleitzke, Tazio   +3 more
core   +1 more source

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