Results 111 to 120 of about 2,569,962 (358)

Cutaneous Adverse Events Following Nemolizumab Administration: A Review

Journal of Clinical Medicine
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction and immune dysregulation, with interleukin (IL)-4, IL-13, and IL-31 recognized as key mediators. Prurigo nodularis (PN) is another chronic inflammatory disorder driven by T helper type 2-mediated inflammation and neural dysregulation, leading to
Yoshihito Mima, Masako Yamamoto, Ken Iozumi   +2 more
openaire   +2 more sources

A Novel Sprayable Fibrinogen/Glycosaminoglycans/Collagen‐Based Bioink for Skin Wound Healing Applied by a Handheld Dual‐Head Airbrush

Advanced Healthcare Materials, EarlyView.
A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán, Daniel Nieto‐García, Carlos Chocarro‐Wrona, Juan de Vicente, Patricia Gálvez‐Martín, José Manuel Entrena, Elena López‐Ruiz, Juan Antonio Marchal   +7 more
wiley   +1 more source

Cutaneous and renal glomerular vasculopathy as a cause of acute kidney injury in dogs in the UK [PDF]

, 2015
To describe the signalment, clinicopathological findings and outcome in dogs presenting with acute kidney injury (AKI) and skin lesions between November 2012 and March 2014, in whom cutaneous and renal glomerular vasculopathy (CRGV) was suspected and ...
ARDISSINO, ARDISSINO, ARONSON, BIRNBAUM, BLOMBERY, BOURHY, BOYCE, BURNENS, CARPENTER, CHANTREY, COWAN, DELL'ORCO, DICKINSON, EUBIG, FERRER, FISCHER, FOURNEL, GARCIA, GOLDFARB, GREENE, HENDRICKS, HERTZKE, HOLLOWAY, KAVANAGH, LI, MILFORD, MONAHAN, MOORE, MORRIS, MUNDAY, NORIS, PASS, REBAR, RENTKO, ROBY, ROTERMUND, RUGGENENTI, SALVADORI, SYKES, TANGEMAN, TARR, TARR, UCHIDA, VAN DEN INGH, VICTORIA, WAIKAR, WALKER   +46 more
core   +1 more source

Exosome‐Guided Phenotypic Switch of M1 to M2 Macrophages for Cutaneous Wound Healing

Advancement of science, 2019
Macrophages (Mϕs) critically contribute to wound healing by coordinating inflammatory, proliferative, and angiogenic processes. A proper switch from proinflammatory M1 to anti‐inflammatory M2 dominant Mϕs accelerates the wound healing processes leading ...
Hyosuk Kim, Sun Young Wang, Gijung Kwak, Yoosoo Yang, I. Kwon, Sun Hwa Kim   +5 more
semanticscholar   +1 more source

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri, Renata Maia, Pei Zhang, Liliana Agresti, Jelmer Sjollema, Mohammad‐Ali Shahbazi, Hélder A. Santos   +6 more
wiley   +1 more source

NGF and therapeutic prospective: what have we learned from the NGF transgenic models?

Annali dell'Istituto Superiore di Sanità, 2015
It has been shown that topical nerve growth factor (NGF) administration induces healing action on human cutaneous, corneal and pressure ulcers, glaucoma, maculopathy and retinitis pigmentosa suggesting a therapeutic potential of NGF in human ...
Luigi Aloe, Maria Luisa Rocco
doaj   +1 more source

An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice [PDF]

, 2013
Interleukin (IL)-33, the most recent member of the IL family of cytokines, signals through the ST2 receptor. IL-33/ST2 signaling mediates antigen challenge-induced mechanical hyperalgesia in the joints and cutaneous tissues of immunized mice. The present
Alves-Filho, J.C., Casagrande, R., Cunha, F.Q., Cunha, T.M., Ferreira, S.H., Hohmann, M.S.N., Liew, F.Y., Magro, D.A.C., Mizokami, S.S., Verri Jr, W.A.   +9 more
core   +3 more sources

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

Advanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa, Ana B. Carneiro, Filipa Lebre, João Meneses, Alar Ainla, Cacilda Moura, Ernesto Alfaro‐Moreno, Ana R. Ribeiro   +7 more
wiley   +1 more source

Transdermal drug delivery treatment for overactive bladder

International Brazilian Journal of Urology, 2006
Overactive bladder is commonly treated with oral anticholinergic drugs such as oxybutynin chloride. Although oral anticholinergic agents have been effective in controlling urinary urgency and incontinence, adverse events, particularly dry mouth, often ...
Roger R. Dmochowski, Jonathan S. Starkman, G. Willy Davila   +2 more
doaj   +1 more source

Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]

, 2020
Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L, Crew, Ashley, DeClerck, Brittney, Guzman, Ruben, Peng, David   +4 more
core