Results 31 to 40 of about 2,569,962 (358)

Cutaneous Adverse Events in Newly Approved FDA Non-cancer Drugs: A Systematic Review

Drugs in R&D, 2020
The prevalence of cutaneous adverse events attributable to newly approved anti-cancer drugs has been well reviewed in the dermatologic literature. In contrast, over 75% of US Food and Drug Administration approvals in the past 5 years have been for non ...
Paul C. Macklis, Brittany Dulmage, Brady Evans, Misha Rosenbach, Johann E. Gudjonsson, Benjamin H. Kaffenberger   +5 more
doaj   +1 more source

Repeated Treatment With the Traditional Medicine Unsei-in Inhibits Substance P-Induced Itch-Associated Responses Through Downregulation of the Expression of Nitric Oxide Synthase 1 in Mice

Journal of Pharmacological Sciences, 2004
Unsei-in inhibits substance P (SP)-induced scratching of mice after repeated administration. The involvement of cutaneous nitric oxide (NO) in the SP-induced scratching led us to investigate the effects of Unsei-in on the cutaneous NO system in mice ...
Tsugunobu Andoh, Ali Al-Akeel, Kenichiro Tsujii, Hiroshi Nojima, Yasushi Kuraishi   +4 more
doaj   +1 more source

Serum Level of Soluble CD163 May Be a Predictive Marker of the Effectiveness of Nivolumab in Patients With Advanced Cutaneous Melanoma

Frontiers in Oncology, 2018
Antibodies against programmed cell death protein 1, such as nivolumab and pembrolizumab, are widely used for treating various cancers, including advanced melanoma.
Taku Fujimura, Yota Sato, Kayo Tanita, Yumi Kambayashi, Atsushi Otsuka, Yasuhiro Fujisawa, Koji Yoshino, Shigeto Matsushita, Takeru Funakoshi, Hiroo Hata, Yuki Yamamoto, Hiroshi Uchi, Yumi Nonomura, Ryota Tanaka, Megumi Aoki, Keisuke Imafuku, Hisako Okuhira, Naoko Wada, Hiroyuki Irie, Takanori Hidaka, Akira Hashimoto, Setsuya Aiba   +21 more
doaj   +1 more source

Combined pulsed-dye laser and medical therapy for treatment of cutaneous sarcoidosis lesions: a case report

Journal of International Medical Research, 2021
Sarcoidosis is a systemic granulomatous disease of unknown etiology that most frequently occurs in the lungs. However, cutaneous lesions are often the primary sign.
Wenxin Dong, Caixia Li, Yu Shi, Wei Zhang   +3 more
doaj   +1 more source

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [PDF]

, 2019
Background: The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory approval.
Buti, S, Cappuzzo, F, Cartenì, G, Cognetti, F, Cortesi, E, De Giglio, A, De Giorgi, U, Giannarelli, D, Panni, S, Pazzola, A, Porta, C, Procopio, G, Raimondi, A, Rastelli, F, Rossetti, S, Sabbatini, R, Sobrero, A, Sternberg, Cn, Surico, G, Tassinari, D, Tortora, G, Turci, D, Verzoni, E   +22 more
core   +3 more sources

A Case of Bowen’s Disease and Small-Cell Lung Carcinoma: Long-Term Consequences of Chronic Arsenic Exposure in Chinese Traditional Medicine [PDF]

, 2004
Chronic arsenic toxicity occurs primarily through inadvertent ingestion of contaminated water and food or occupational exposure, but it can also occur through medicinal ingestion.
Castren K, Gwyn Bebb, Hutchison J, Jaeger AB, Linda Lee, Mazumder DN, Tay CH, Tseng WP, Wong ST   +8 more
core   +2 more sources

Bimodal Feedback for In-car Mid-air Gesture Interaction [PDF]

, 2017
This demonstration showcases novel multimodal feedback designs for in-car mid-air gesture interaction. It explores the potential of multimodal feedback types for mid-air gestures in cars and how these can reduce eyes-off-the-road time thus make driving ...
Brewster, Stephen A., Shakeri, Gözel, Williamson, John H.   +2 more
core   +1 more source

Modulation of Neurally Mediated Vasodepression and Bradycardia by Electroacupuncture through Opioids in Nucleus Tractus Solitarius. [PDF]

, 2018
Stimulation of vagal afferent endings with intravenous phenylbiguanide (PBG) causes both bradycardia and vasodepression, simulating neurally mediated syncope.
Fu, Liang-Wu, Guo, Zhi-Ling, Longhurst, John C, Tjen-A-Looi, Stephanie C   +3 more
core   +3 more sources

Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. [PDF]

, 2013
Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver ...
Blecher-Paz, Karin, Champer, Jackson, Friedman, Adam J, Kim, Jenny, Liu, Phil T, Modlin, Robert L, Oren, Ami, Phan, Jenny, Pirouz, Aslan, Qin, Min, Schairer, David O   +10 more
core   +1 more source

Next-Generation Wound Care: A Scoping Review on Probiotic, Prebiotic, Synbiotic, and Postbiotic Cutaneous Formulations

Pharmaceuticals
Background/Objectives: Chronic wounds represent a significant socioeconomic burden, affecting 1–2% of the global population. Wound healing is a complex process involving inflammation, cell proliferation, and tissue remodeling, but factors such as ...
Patrícia Machado, Felipe Neme Ribeiro, Fernanda Cristina Wroblevski Giublin, Naomi Gerzvolf Mieres, Fernanda Stumpf Tonin, Roberto Pontarolo, Marcel Henrique Marcondes Sari, Raul Edison Luna Lazo, Luana Mota Ferreira   +8 more
doaj   +1 more source