Characteristics and application of cutaneous spray preparations in dermal and transdermal drug delivery [PDF]
Liquid spray preparations for cutaneous administration are solutions, suspensions or emulsions that use compressed or converted gas to a liquid state, to disperse the active substance in the form of aerosols or they are propellant-free (not pressurized ...
Đekić Ljiljana +2 more
doaj +1 more source
Pemphigus is an autoimmune mucocutaneous blistering disease caused by autoantibodies against desmogleins. Rituximab effectively treats pemphigus by inducing remission and rapidly reducing corticosteroid dosage.
Ahreum Song +8 more
doaj +1 more source
Immunization with antigenic extracts of Leishmania associated with Montanide ISA 763 adjuvant induces partial protection in BALB/c mice against Leishmania (Leishmania) amazonensis infection [PDF]
Background/Purpose: A proper adjuvant has a relevant role in vaccine formulations to generate an effective immune response. In this study, total Leishmania antigen (TLA) formulated with Montanide ISA 763 or R848 as adjuvants were evaluated as a first ...
Cargnelutti, Diego Esteban +6 more
core +1 more source
The standard of care for cutaneous leishmaniasis includes the intramuscular/intravenous administration of pentavalent antimonials that are toxic and poorly tolerated.
Ernesto Rojas Cabrera +9 more
doaj +1 more source
Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure [PDF]
Air pollution is linked to increased emergency department visits for headache and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood.
Hurley, Joyce Harts +4 more
core +1 more source
Cutaneous Pseudolymphoma Following Administration of Lornoxicam
Since aspirin was introduced over a century ago, many new anti-inflammatory agents have been marketed. NSAIDs are currently the most commonly prescribed agents in Western medicine (1). Their widespread use has resulted in a number of well-documented adverse reactions. These most frequently involve the gastro-intestinal tract, causing discomfort, nausea
Stavrianeas, N.G. +7 more
openaire +3 more sources
Phase II evaluation of VDC-1101 in canine cutaneous T-cell lymphoma. [PDF]
BackgroundCanine cutaneous T-cell lymphoma (CTCL) is an uncommon disease for which efficacious therapies are lacking. The novel anticancer nucleotide prodrug VDC-1101 (formerly known as GS-9219) has shown efficacy in dogs with multicentric lymphoma.
Burgess, KE +5 more
core +2 more sources
Cutaneous Adverse Events in Newly Approved FDA Non-cancer Drugs: A Systematic Review
The prevalence of cutaneous adverse events attributable to newly approved anti-cancer drugs has been well reviewed in the dermatologic literature. In contrast, over 75% of US Food and Drug Administration approvals in the past 5 years have been for non ...
Paul C. Macklis +5 more
doaj +1 more source
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]
BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
Dawkins, RS +5 more
core +1 more source
Acute Hepatic Porphyrias: Review and Recent Progress. [PDF]
The acute hepatic porphyrias (AHPs) are a group of four inherited diseases of heme biosynthesis that present with episodic, acute neurovisceral symptoms.
Andant +40 more
core +1 more source

