Results 51 to 60 of about 145,153 (301)

Synthesis and antiprotozoal evaluation of new N4-(benzyl)spermidyl-linked bis(1,3,5-thiadiazinane-2-thiones).

, 2008
The synthesis and in-vitro antiprotozoal evaluation of novel N(4)-(benzyl)spermidyl-linked bis(1,3,5-thiadiazinane-2-thione) (bis-THTT) derivatives from N(4)-(benzyl)spermidine is disclosed. Several of the new bis-THTT have in-vitro activities against L.
Julieta Coro, Little, Susan, Perez-Pineiro, Rolando, Hortensia Rodríguez, Coro, Julieta, Suárez, Margarita, Martín, Nazario, Vanessa Yardley, Nazario Martín, Yardley, Vanessa, Margarita Suárez, Rolando Perez‐Pineiro, Susan Little, Rodríguez, Hortensia   +13 more
core   +1 more source

The effect of 17β-estradiol on cutaneous wound healing in protein-malnourished ovariectomized female mouse model.

PLoS ONE, 2014
Cutaneous wound healing is delayed by protein malnutrition (PM). On the other hand, estrogen promotes cutaneous wound healing by its anti-inflammatory and cell proliferation effects.
Kanae Mukai, Emi Komatsu, Yukari Nakajima, Tamae Urai, Nasruddin, Junko Sugama, Toshio Nakatani   +6 more
doaj   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Frequency of cutaneous necrosis among patients who did and did not receive anti-arachnid serum, by the time from bite to antivenom administration.

, 2022
Frequency of cutaneous necrosis among patients who did and did not receive anti-arachnid serum, by the time from bite to antivenom administration.
Christina T. G. Novaes (13961817), Karina T. Miyaji (3394292), Ceila M. S. Malaque (13961814), Jose Y. Risk (13961823), Amanda N. Lara (13961829), Cristiana C. Virgulino (13961832), Jefferson C. Murad (13961826), Marcelo L. Santoro (10711502), Roberta O. Piorelli (13961820)   +8 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Life-threatening rocuronium-induced anaphylactic shock without cutaneous manifestations successfully reversed with sugammadex: a case report

JA Clinical Reports, 2020
Background Recognition of rocuronium-induced anaphylaxis is often challenging, owing to its diverse clinical manifestations. Regarding treatment, several reports have described the efficacy of sugammadex, while conflicting reports have also been ...
Yoshiaki Takise, Jungo Kato, Tomohiro Suhara, Takashige Yamada, Takeru Funakoshi, Hayato Takahashi, Masayuki Amagai, Hiroshi Morisaki   +7 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Pharmacokinetics and concentration-effect relationship of oral LSD in humans [PDF]

, 2015
BACKGROUND: The pharmacokinetics of oral lysergic acid diethylamide are unknown despite its common recreational use and renewed interest in its use in psychiatric research and practice.
Dolder, Patrick C., Rentsch, Katharina M., Liechti, Matthias E., Schmid, Yasmin, Haschke, Manuel   +4 more
core   +1 more source

Hospital Pharmacy and Research

CHIMIA, 2006
Hospital pharmacies play a crucial role in managing and/or accompanying the entire drug handling process, from the drug's origin all the way through the hospital system to the patient, and to promote rational and appropriate drug use.
Christian Surber, Carolina Pellanda, Katja Zimmermann, Manuela Endres, Verena Figueiredo, Roland Werner, Herbert Plagge, Ruth Leu Marseiler   +7 more
doaj   +1 more source

Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males

Journal of Translational Medicine, 2022
Background We hypothesized that a gender difference in clinical response may exist to adjuvant CTLA4 blockade with ipilimumab versus high-dose IFNα (HDI).
Mariam Saad, Sandra J. Lee, Aik Choon Tan, Issam M. El Naqa, F. Stephen Hodi, Lisa H. Butterfield, William A. LaFramboise, Walter Storkus, Arivarasan D. Karunamurthy, Jose Conejo-Garcia, Patrick Hwu, Howard Streicher, Vernon K. Sondak, John M. Kirkwood, Ahmad A. Tarhini   +14 more
doaj   +1 more source