Results 41 to 50 of about 196,170 (224)

Treating cutaneous leishmaniasis patients in Kabul, Afghanistan: cost-effectiveness of an operational program in a complex emergency setting. [PDF]

, 2007
BACKGROUND: Although Kabul city, Afghanistan, is currently the worldwide largest focus of cutaneous leishmaniasis (CL) with an estimated 67,500 cases, donor interest in CL has been comparatively poor because the disease is non-fatal. Since 1998 HealthNet
Reithinger, Richard, Coleman, Paul G, Reithinger Richard, Richard Reithinger, Coleman Paul G, Paul G Coleman   +5 more
core   +2 more sources

Assessment of Leishmaniasis notification system in Santiago del Estero, Argentina, 1990-1993. [PDF]

, 2001
Using a capture-recapture method, this study evaluates the completeness of the cutaneous leishmaniasis (CL) surveillance system in four districts of Santiago del Estero province, Argentina, for the period 1990-1993. Four reporting sources were evaluated:
Yadón, ZE, E L Segura, Z E Yadón, Yadón, Zaida E., L C Rodrigues, Quigley, MA, Davies, CR, Rodrigues, LC, C R Davies, Segura, Elsa L., Segura, Elsa Leonor, Quigley, Maria A., Quigley, Maria, M A Quigley, Rodrigues, Laura C., Davies, Clive R., Segura, EL   +16 more
core   +1 more source

The transmission dynamics of canine American cutaneous leishmaniasis in Huánuco, Peru. [PDF]

, 2003
The epidemiology of canine American cutaneous leishmaniasis (ACL) due to Leishmania (Viannia) spp. was investigated in Huánuco, Peru to 1) describe the natural course of canine L.
Reithinger, Richard, Espinoza, Juan Canales, Davies, Clive R   +2 more
core   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Multiple hybrid genotypes of Leishmania (viannia) in a focus of mucocutaneous Leishmaniasis. [PDF]

, 2007
The principal agent of mucocutaneous leishmaniasis (MCL) is the South American protozoan parasite Leishmania (Viannia) braziliensis. This organism is generally considered to be clonal, that is, it does not to undergo genetic exchange.
Miles, Michael A, Roncal, Norma, Nolder, Debbie, Llanos-Cuentas, Alejandro, Davies, Clive R   +4 more
core   +1 more source

Artificial Intelligence in Dermatology: Current Applications and Future Directions

JEADV Clinical Practice, EarlyView.
This scoping review of 56 studies maps AI applications in dermatology. Image‐based classification for skin cancer detection dominates (48%), followed by clinical decision support (21%), teledermatology triage (11%), and predictive analytics (11%). While deep learning algorithms demonstrate diagnostic performance comparable to clinicians in controlled ...
Sofía Pérez‐Lalinde, Francisco Flores   +1 more
wiley   +1 more source

Structures, targets and recent approaches in anti-leishmanial drug discovery and development. [PDF]

, 2011
Recent years have seen a significant improvement in available treatment options for leishmaniasis. Two new drugs, miltefosine and paromomycin, have been registered for the treatment of visceral leishmaniasis (VL) in India since 2002.
Karin Seifert, Seifert, Karin
core   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

The sandfly vectors and epidemiology of cutaneous leishmaniasis in the Landazury Focus, Colombia. [PDF]

This thesis describes a comprehensive cohort study of cutaneous leishmaniasis (CL) in a population of 2,704 followed over a period of 19 months, in the Opon focus, Landazury, Santander, Colombia.
Munoz-Mantilla, Gerardo
core   +1 more source

Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg, Dennis Wienand, Lucie Harpain, Marie‐Luise Brunner‐Kovarik, Julia Walochnik, Markus Wiesmueller, Amélie Hampel, Tibor Spath, Lukas Trnka, Judit Simon, Alessandra Handisurya   +10 more
wiley   +1 more source