Results 91 to 100 of about 28,538 (266)

Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang   +3 more
wiley   +1 more source

Dermatology 2.0: Precision medicine for inflammatory skin diseases

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio   +4 more
wiley   +1 more source

Serum galectin-3 and galectin-3 binding protein levels in systemic lupus erythematosus and cutaneous lupus erythematosus [PDF]

open access: gold, 2020
Agnieszka Kalińska‐Bienias   +5 more
openalex   +1 more source

Litifilimab efficacy on skin outcomes in cutaneous lupus erythematosus in the Phase 2 LILAC study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Our findings show that greater proportions of litifilimab‐treated participants than placebo experienced 20%, 50%, 70% or 90% improvements in CLASI‐A score from baseline and CLASI‐A scores of 0–1 or 0–3. Similar results were observed using physician global assessments, supporting the Phase 2 LILAC study primary analysis in CLE.
Victoria P. Werth   +8 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Indexes of skin activity and damage in patients with systemic lupus erythematosus – CLASI and R-CLASI

open access: yesНаучно-практическая ревматология
Introduction. Cutaneous Lupus Disease Area and Severity Index (CLASI) and its modified version, the Revised Cutaneous Lupus Erythematosus Disease Areas and Severity Index (R-CLASI) are tools for quantifying skin and mucosal lesions in patients with both ...
А. А. Shumilova   +4 more
doaj   +1 more source

Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case–Control Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To analyze the association between oral lichen planus (OLP), oral lichenoid lesions (OLL), and other comorbidities. Material and Methods A case–control study of 205 OLP, 96 OLL patients, and 301 age‐ and sex‐matched controls from Kuopio University Hospital was performed.
Mari Vehviläinen   +3 more
wiley   +1 more source

Acne Vulgaris Mimicking Cutaneous Lupus Erythematosus in an Adolescent: Report of a Rare Case [PDF]

open access: gold, 2021
Irma Bernadette S. Sitohang   +4 more
openalex   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

open access: yesPhotochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio   +4 more
wiley   +1 more source

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