Optics-less smart sensors and a possible mechanism of cutaneous vision in nature [PDF]
Optics-less cutaneous (skin) vision is not rare among living organisms, though its mechanisms and capabilities have not been thoroughly investigated. This paper demonstrates, using methods from statistical parameter estimation theory and numerical simulations, that an array of bare sensors with a natural cosine-law angular sensitivity arranged on a ...
arxiv +1 more source
This review seeks to provide a thorough synthesis of the existing literature on the role of thrombopoietin receptor agonists in the treatment of primary and secondary immune thrombocytopenia, with particular emphasis on the compound Hetrombopag. Abstract Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by a platelet count below
Jiaqi Hu+8 more
wiley +1 more source
Tumid lupus erythematosus is an uncommon subtype of chronic cutaneous lupus erythematosus. Hereby, we report a 36-year-old male patient with tumid lupus erythematosus who presented with erythematous papules and plaques on the face and neck who showed ...
Funda Tamer+3 more
doaj +1 more source
Autologous Fat Transfer in a Patient with Lupus Erythematosus Profundus
Lupus erythematosus profundus, a form of chronic cutaneous lupus erythematosus, is a rare inflammatory disease involving in the lower dermis and subcutaneous tissues. It primarily affects the head, proximal upper arms, trunk, thighs, and presents as firm
Jimi Yoon+5 more
doaj +1 more source
Integrated machine learning pipeline for aberrant biomarker enrichment (i-mAB): characterizing clusters of differentiation within a compendium of systemic lupus erythematosus patients [PDF]
Clusters of differentiation (CD) are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies (mAB) afford rich trans-disease repositioning opportunities. Within a compendium of systemic lupus erythematous (SLE) patients, we applied the Integrated machine ...
arxiv
Lupus Erythematosus: Cutaneous Manifestations and Treatment
Cutaneous lupus erythematosus (CLE) includes a broad range of dermatologic manifestations, which may or may not be associated with systemic manifestations. Specific CLE - defined by the presence of an interface dermatitis on histopathological evaluation -
Francisca Alves, Margarida Gonçalo
doaj +1 more source
How scientific literature has been evolving over the time? A novel statistical approach using tracking verbal-based methods [PDF]
This paper provides a global vision of the scientific publications related with the Systemic Lupus Erythematosus (SLE), taking as starting point abstracts of articles. Through the time, abstracts have been evolving towards higher complexity on used terminology, which makes necessary the use of sophisticated statistical methods and answering questions ...
arxiv
Classification on Large Networks: A Quantitative Bound via Motifs and Graphons [PDF]
When each data point is a large graph, graph statistics such as densities of certain subgraphs (motifs) can be used as feature vectors for machine learning. While intuitive, motif counts are expensive to compute and difficult to work with theoretically. Via graphon theory, we give an explicit quantitative bound for the ability of motif homomorphisms to
arxiv
Multigene Next-Generation Sequencing Panel Identifies Pathogenic Variants in Patients with Unknown Subtype of Epidermolysis Bullosa: Subclassification with Prognostic Implications [PDF]
Purpose: Epidermolysis bullosa (EB), the prototype of heritable blistering diseases, is caused by mutations in as many as 19 distinct genes. In this study, we evaluated the molecular basis of EB in 93 families, many of them of unknown subtype. Methods:
Abiri, Maryam+15 more
core +1 more source
A Guide to Screening for Autoimmune Diseases in Patients With Vulvar Lichen Sclerosus
ABSTRACTBackgroundThe aetiology of vulvar lichen sclerosus (VLS) remains unknown. However, there is evidence that in addition to a genetic predisposition, autoimmunity contributes to the pathogenesis.ObjectivesThe objective of this study was to determine the prevalence of autoimmune disease and positive autoantibody serology in patients with VLS ...
Annabel Guttentag+5 more
wiley +1 more source