Case series of anifrolumab for treatment of cutaneous lupus erythematosus and lupus-related mucocutaneous manifestations in patients with SLE [PDF]
Objective To assess the efficacy of anifrolumab, a type-1 interferon receptor subunit-1 monoclonal antibody, in treating refractory cutaneous lupus erythematosus (CLE) and lupus non-specific mucocutaneous manifestations in patients with systemic lupus ...
Jun Kang, Aaron Bao
doaj +2 more sources
Cutaneous lupus erythematosus: a review of etiopathogenic, clinical, diagnostic and therapeutic aspects [PDF]
Cutaneous lupus erythematosus is an autoimmune disease of varied clinical expression, which may present as an exclusively cutaneous disease or be one of the multiple manifestations of systemic lupus erythematosus.
Everton Carlos Siviero do Vale+1 more
doaj +2 more sources
Subacute cutaneous lupus erythematosus with a psoriasiform presentation: A diagnostic clinical conundrum [PDF]
Key Clinical Message For practitioners experiencing worsening psoriasis, subacute cutaneous lupus erythematosus (SCLE) with a psoriasiform presentation should be ruled out.
Shazli Razi+4 more
doaj +2 more sources
Manifestation of subacute cutaneous lupus erythematosus during treatment with anti-PD-1 antibody cemiplimab – a case report [PDF]
IntroductionThe anti-programmed cell death protein 1 (PD-1) antibody cemiplimab has shown promising results in the treatment of unresectable or metastatic squamous cell carcinoma, however, frequently leads to immune-related adverse events limiting ...
Simon Fietz+8 more
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Objective Lupus erythematosus (LE) is a complicated disease with highly heterogeneous clinical manifestations. Previous studies have rarely included all subgroups of patients with lupus and have overlooked the importance of the cutaneous manifestations ...
Qing Zhang+19 more
doaj +1 more source
Sex differences in lymphoma incidence and mortality by subtype: A population‐based study
A higher incidence and a trend toward higher mortality in men for most lymphoma subtypes is seen in this Swedish population‐based cohort study on adults (age 18‐99) diagnosed with lymphoma 2000‐2019. Male‐to‐female incidence rate ratio (IRR) by male‐to‐female excess mortality ratio (EMR), both adjusted for age and year of diagnosis, by lymphoma subtype.
Cecilia Radkiewicz+9 more
wiley +1 more source
JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana+5 more
core +20 more sources
Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects [PDF]
Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new ...
Jucelio Pereira Moura Filho+6 more
doaj +1 more source
Abstract The aim of this study was to examine potential synergistic effects between maternal autoimmune disease and early childhood infections and their association with autism spectrum disorder (ASD) in offspring. Both exposures have been associated with increased risk of ASD in previous studies, but potential synergistic effects remain underexplored.
Timothy C. Nielsen+8 more
wiley +1 more source
We investigated 85 patients on the relationship between the axon reflex sweat volume or the reaction time and Raynaud's phenomenon, skin symptoms and patient background. Most patients did not show a decrease in sweating, but one in three patients showed less sweating in summer than in winter.
Miwa Ashida+5 more
wiley +1 more source