Results 191 to 200 of about 27,354 (241)
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Chronic Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1989Chronic cutaneous LE is a diverse disease, characterized by predominantly cutaneous disease with few systemic complications. Discoid lesions are commonly seen, but they are not specific for chronic cutaneous LE. These scarring and disfiguring changes are also present in neonatal LE, SLE, and complement deficiency LE. Because definitive diagnosis cannot
S R, Hymes, R E, Jordon
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Treatment of cutaneous lupus erythematosus
Lupus, 2010In patients with cutaneous lupus erythematosus (CLE) and mild skin involvement, local therapy consisting of topically applied pharmacological agents, e.g., topical/intralesional steroids, may be sufficient. Recent reports have also shown efficacy of topical calcineurin inhibitors in patients with CLE, particularly on the face ...
A, Kuhn, F, Ochsendorf, G, Bonsmann
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Thalidomide in Cutaneous Lupus Erythematosus
American Journal of Clinical Dermatology, 2003For nearly 50 years, thalidomide has struggled between success and controversy. After causing an epidemic of phocomelia and other birth defects during the 1960s, affecting thousands of neonates, thalidomide was used as a sedative in selective disorders including leprosy.
Michelle T, Pelle, Victoria P, Werth
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Seminars in Cutaneous Medicine and Surgery, 2001
Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Therapy of Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1982Cutaneous lupus erythematosus occurs in a spectrum from limited cutaneous disease to severe systemic disease. Chronic DLE generally follows a benign course, but rare transformation to systemic disease may occur. Subacute cutaneous LE is associated with a specific cutaneous lesion and mild to moderate systemic symptoms.
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Pathogenesis of cutaneous lupus erythematosus
Lupus, 2008Although for decades sunlight was suspected to be involved in the development of cutaneous lupus erythematosus (CLE), only in recent years research on the effects of ultraviolet irradiation on the skin of patients with CLE has resulted in a more comprehensive model for the pathogenesis of the disease.
Kuhn, A., Bijl, M.
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The Immunopathology of Cutaneous Lupus Erythematosus
Rheumatic Disease Clinics of North America, 2014Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the development of autoantibodies and immunologic attack of different organ systems, including the skin. This review aims to provide an overview of some of the pathogenic processes that may be important in the development of SLE, specifically cutaneous lupus ...
Mark G, Kirchhof, Jan P, Dutz
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CUTANEOUS MANIFESTATIONS OF LUPUS ERYTHEMATOSUS
Rheumatic Disease Clinics of North America, 1994Lupus erythematosus is an autoimmune disease that demonstrates cutaneous, systemic, or both cutaneous and systemic manifestations. This article reviews the cutaneous manifestations of lupus erythematosus.
S D, Laman, T T, Provost
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Management of cutaneous lupus erythematosus
Clinics in Dermatology, 1985Abstract Therapy of cutaneous lupus erythematosus is both an art and a science. The interplay of cosmetic and systemic factors must be understood and managed by the physician, who must, following recognition and diagnosis of the problem, discuss prognosis and life-style modification with the patient. Extensive reassurance usually is necessary.
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Pathophysiology of Cutaneous Lupus Erythematosus
Clinical Reviews in Allergy & Immunology, 2007Cutaneous lupus erythematosus (LE; syn LE-specific skin disease) is an autoimmune disease with well-defined skin manifestations often accentuated in a photodistribution and frequently associated with specific autoantibodies. These clinical observations have led to numerous laboratory studies related to the role of ultraviolet light, as well as studies ...
Julie H, Lin +3 more
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