Results 201 to 210 of about 27,354 (241)
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Subacute cutaneous lupus erythematosus

2000
Subacute cutaneous lupus erythematosus (SCLE) represents a relatively distinct and homogeneous subset of lupus erythematosus (LE) identified by chronic and recurrent development of characteristic erythematous, non-scarring and mostly photosensitive skin lesions associated with particular clinical, immunological and genetic features.
M. N. Manoussakis, H. M. Moutsopoulos
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Histopathology of cutaneous lupus erythematosus

Clinics in Dermatology, 1985
The basic histopathologic feature of all cutaneous lesions of lupus erythematosus involves a perivascular mononuclear cell infiltrate with subsequent involvement of the epidermis and appendages. The various histologic alterations affecting the epidermis, dermis, and adnexal structures reflect the particular type of lesion biopsied and the duration of ...
A F, Hood, E R, Farmer
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Subacute cutaneous lupus erythematosus

Journal of the Royal Army Medical Corps, 2016
A 31-year-old female soldier developed subacute cutaneous lupus erythematosus, which remained undiagnosed for 4 years. Referral to dermatology and a punch biopsy confirmed the diagnosis and effective treatment was instituted. The presence of an unresolving annular rash in light-exposed areas, especially in a young woman, should prompt thorough ...
Jacqueline, Furzeland, P, Malcolm
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Cutaneous lupus erythematosus: a review

Dermatologic Clinics, 2002
This article will review and update information about the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus. Lupus erythematosus (LE) can present as a skin eruption, with or without systemic disease. Cutaneous LE is subdivided into chronic cutaneous LE, subacute cutaneous LE and acute LE.
Purvisha, Patel, Victoria, Werth
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Neonatal cutaneous lupus erythematosus

Archives of Disease in Childhood - Fetal and Neonatal Edition, 2018
A full-term baby girl born to a seemingly healthy mother presented at birth with an atrophic and erythematous scaly rash on her face (figure 1A) and multiple atrophic ill-defined scars distributed mainly over scalp, chest and back (figure 1B). Absence of eyebrows and eyelashes was also noted. The immune and autoimmune study was requested and both …
Henar, Romero Rey   +1 more
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Pathogenesis of cutaneous lupus erythematosus

Clinics in Dermatology, 1985
Antibody-dependent mechanisms of tissue damage are the principle mechanism of disease in systemic and cutaneous lupus erythematosus. Antibody-dependent mechanisms of keratinocyte damage appear to be a primary pathogenetic factor in all forms of papulosquamous cutaneous lupus. Photosensitive papulosquamous lupus syndromes, such as subacute cutaneous LE,
D A, Norris, L A, Lee
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Cutaneous Lupus Erythematosus

American Journal of Clinical Dermatology, 2009
Cutaneous lupus erythematosus (LE) may present in a variety of clinical forms. Three recognized subtypes of cutaneous LE are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE), and chronic cutaneous LE (CCLE). ACLE may be localized (most often as a malar or 'butterfly' rash) or generalized.
Hobart W, Walling, Richard D, Sontheimer
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Immunology of cutaneous lupus erythematosus

Clinics in Dermatology, 2004
The cause and effect between ultraviolet light and cutaneous lupus erythematosus (CLE) is clear. In LE patients indeed, photosensitivity is one of the major diagnostic criteria of the systemic form of lupus erythematosus. This strong clinical association has led to the postulate that abnormal photosensitivity participates in the pathogenesis of ...
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Subacute cutaneous lupus erythematosus

Clinics in Dermatology, 1985
Abstract A large part of James N. Gilliam's abbreviated investigative career was devoted to testing a hypothesis that strong relationships do exist between the cutaneous and systemic manifestations of lupus erythematosus (LE). As a result of clinical observations made during his early studies designed to test this hypothesis, he introduced the term ...
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Animal models of cutaneous lupus erythematosus and lupus erythematosus photosensitivity

Lupus, 1997
Over the past decade, the most exciting and important finding in SLE-prone mice is the discovery of Fas/Fas ligand systems in the pathogenesis of autoimmune phenomena. A human model for murine lpr/gld disease has also been reported recently. Furthermore, as shown in Table 2, studies on Ig variable region genes, TCR genes and MHC class II genes have ...
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