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Proposal of a cutaneous lupus erythematosus-like keratinocyte model in vitro under local conditions using interferon-alpha and Poly I:C and its use in examining the therapeutic effects of tyrosine kinase 2 inhibitor. [PDF]
J DermatolKuba-Fuyuno Y +4 more
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Cutaneous Lupus Erythematosus in Children
Current Pediatric Reviews, 2021Background:The skin is commonly involved in autoimmune diseases, such as lupus erythematous. The cutaneous lupus erythematosus (CLE) can manifest with or without systemic symptoms. It is advantageous from a patient and healthcare system standpoint for early diagnosis and intervention. Prevention of complications is especially important in the pediatric
Vivian Tsang +2 more
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The Cutaneous Spectrum of Lupus Erythematosus
Clinical Reviews in Allergy & Immunology, 2017Systemic lupus erythematosus is a complex autoimmune disease with a wide spectrum of clinical and immunopathological features. Cutaneous and articular manifestations are the most common signs in patients with systemic lupus erythematosus. We here review the pathogenesis and the new classification of cutaneous lupus erythemathosus with a discussion of ...
Ribero, Simone +3 more
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Pathogenesis of cutaneous lupus erythematosus
Lupus, 2008Although for decades sunlight was suspected to be involved in the development of cutaneous lupus erythematosus (CLE), only in recent years research on the effects of ultraviolet irradiation on the skin of patients with CLE has resulted in a more comprehensive model for the pathogenesis of the disease.
Marc Bijl, Annegret Kuhn
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Neonatal cutaneous lupus erythematosus [PDF]
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2018 A full-term baby girl born to a seemingly healthy mother presented at birth with an atrophic and erythematous scaly rash on her face (figure 1A) and multiple atrophic ill-defined scars distributed mainly over scalp, chest and back (figure 1B). Absence of eyebrows and eyelashes was also noted. The immune and autoimmune study was requested and both …
Alejandro Avila-Alvarez +1 more
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Treatment of cutaneous lupus erythematosus
Lupus, 2010In patients with cutaneous lupus erythematosus (CLE) and mild skin involvement, local therapy consisting of topically applied pharmacological agents, e.g., topical/intralesional steroids, may be sufficient. Recent reports have also shown efficacy of topical calcineurin inhibitors in patients with CLE, particularly on the face.
Gisela Bonsmann +2 more
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Current Problems in Dermatology, 1989
Abstract Cutaneous lesions of lupus erythematosus (LE) have been classified as specific or nonspecific for LE. Common specific lesions are acute cutaneous lupus erythematosus (ACLE), subacute cutaneous lupus erythematosus (SCLE), and chronic discoid lupus erythematosus (DLE). Acute cutaneous lupus erythematosus typically consists of a transient malar
Kathleen M. David, Lela A. Lee
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Abstract Cutaneous lesions of lupus erythematosus (LE) have been classified as specific or nonspecific for LE. Common specific lesions are acute cutaneous lupus erythematosus (ACLE), subacute cutaneous lupus erythematosus (SCLE), and chronic discoid lupus erythematosus (DLE). Acute cutaneous lupus erythematosus typically consists of a transient malar
Kathleen M. David, Lela A. Lee
openaire +2 more sources