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Seminars in Cutaneous Medicine and Surgery, 2001
Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Thalidomide in Cutaneous Lupus Erythematosus
American Journal of Clinical Dermatology, 2003For nearly 50 years, thalidomide has struggled between success and controversy. After causing an epidemic of phocomelia and other birth defects during the 1960s, affecting thousands of neonates, thalidomide was used as a sedative in selective disorders including leprosy.
Victoria P. Werth, Michelle T. Pelle
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2016
Lupus erythematosus (LE) is an inflammatory autoimmune disease, characterized by a heterogeneous clinical presentation. The skin lesions are one of the most frequent symptoms of the disease and present with a broad spectrum of LE-nonspecific and LE-specific cutaneous manifestations. Therefore, the development of a classification for skin lesions in the
Aysche Landmann +2 more
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Lupus erythematosus (LE) is an inflammatory autoimmune disease, characterized by a heterogeneous clinical presentation. The skin lesions are one of the most frequent symptoms of the disease and present with a broad spectrum of LE-nonspecific and LE-specific cutaneous manifestations. Therefore, the development of a classification for skin lesions in the
Aysche Landmann +2 more
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Therapy of Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1982Cutaneous lupus erythematosus occurs in a spectrum from limited cutaneous disease to severe systemic disease. Chronic DLE generally follows a benign course, but rare transformation to systemic disease may occur. Subacute cutaneous LE is associated with a specific cutaneous lesion and mild to moderate systemic symptoms.
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Subacute cutaneous lupus erythematosus
Journal of the Royal Army Medical Corps, 2016A 31-year-old female soldier developed subacute cutaneous lupus erythematosus, which remained undiagnosed for 4 years. Referral to dermatology and a punch biopsy confirmed the diagnosis and effective treatment was instituted. The presence of an unresolving annular rash in light-exposed areas, especially in a young woman, should prompt thorough ...
Jacqueline Furzeland, P Malcolm
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Chronic Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1989Chronic cutaneous LE is a diverse disease, characterized by predominantly cutaneous disease with few systemic complications. Discoid lesions are commonly seen, but they are not specific for chronic cutaneous LE. These scarring and disfiguring changes are also present in neonatal LE, SLE, and complement deficiency LE. Because definitive diagnosis cannot
Robert E. Jordon, Sharon R. Hymes
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Histopathology of cutaneous lupus erythematosus
Clinics in Dermatology, 1985The basic histopathologic feature of all cutaneous lesions of lupus erythematosus involves a perivascular mononuclear cell infiltrate with subsequent involvement of the epidermis and appendages. The various histologic alterations affecting the epidermis, dermis, and adnexal structures reflect the particular type of lesion biopsied and the duration of ...
Evan R. Farmer, Antoinette F. Hood
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2008
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory autoimmune disorder, comprising a broad spectrum of clinical manifestations. Various environmental factors influence the clinical expression of CLE and a striking relationship has emerged between sunlight exposure and the various subtypes of this disease.
Annegret Kuhn +2 more
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Cutaneous lupus erythematosus (CLE) is a chronic inflammatory autoimmune disorder, comprising a broad spectrum of clinical manifestations. Various environmental factors influence the clinical expression of CLE and a striking relationship has emerged between sunlight exposure and the various subtypes of this disease.
Annegret Kuhn +2 more
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Pathogenesis of cutaneous lupus erythematosus
Clinics in Dermatology, 1985Antibody-dependent mechanisms of tissue damage are the principle mechanism of disease in systemic and cutaneous lupus erythematosus. Antibody-dependent mechanisms of keratinocyte damage appear to be a primary pathogenetic factor in all forms of papulosquamous cutaneous lupus. Photosensitive papulosquamous lupus syndromes, such as subacute cutaneous LE,
David A. Norris, L.A. Lee
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Management of cutaneous lupus erythematosus
Clinics in Dermatology, 1985Abstract Therapy of cutaneous lupus erythematosus is both an art and a science. The interplay of cosmetic and systemic factors must be understood and managed by the physician, who must, following recognition and diagnosis of the problem, discuss prognosis and life-style modification with the patient. Extensive reassurance usually is necessary.
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