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Neonatal cutaneous lupus erythematosus
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2018A full-term baby girl born to a seemingly healthy mother presented at birth with an atrophic and erythematous scaly rash on her face (figure 1A) and multiple atrophic ill-defined scars distributed mainly over scalp, chest and back (figure 1B). Absence of eyebrows and eyelashes was also noted. The immune and autoimmune study was requested and both …
Henar, Romero Rey +1 more
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Pathogenesis of cutaneous lupus erythematosus
Clinics in Dermatology, 1985Antibody-dependent mechanisms of tissue damage are the principle mechanism of disease in systemic and cutaneous lupus erythematosus. Antibody-dependent mechanisms of keratinocyte damage appear to be a primary pathogenetic factor in all forms of papulosquamous cutaneous lupus. Photosensitive papulosquamous lupus syndromes, such as subacute cutaneous LE,
D A, Norris, L A, Lee
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Subacute cutaneous lupus erythematosus
2000Subacute cutaneous lupus erythematosus (SCLE) represents a relatively distinct and homogeneous subset of lupus erythematosus (LE) identified by chronic and recurrent development of characteristic erythematous, non-scarring and mostly photosensitive skin lesions associated with particular clinical, immunological and genetic features.
M. N. Manoussakis, H. M. Moutsopoulos
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Pathophysiology of Cutaneous Lupus Erythematosus
Clinical Reviews in Allergy & Immunology, 2007Cutaneous lupus erythematosus (LE; syn LE-specific skin disease) is an autoimmune disease with well-defined skin manifestations often accentuated in a photodistribution and frequently associated with specific autoantibodies. These clinical observations have led to numerous laboratory studies related to the role of ultraviolet light, as well as studies ...
Julie H, Lin +3 more
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Subacute cutaneous lupus erythematosus
Clinics in Dermatology, 1985Abstract A large part of James N. Gilliam's abbreviated investigative career was devoted to testing a hypothesis that strong relationships do exist between the cutaneous and systemic manifestations of lupus erythematosus (LE). As a result of clinical observations made during his early studies designed to test this hypothesis, he introduced the term ...
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American Journal of Clinical Dermatology, 2009
Cutaneous lupus erythematosus (LE) may present in a variety of clinical forms. Three recognized subtypes of cutaneous LE are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE), and chronic cutaneous LE (CCLE). ACLE may be localized (most often as a malar or 'butterfly' rash) or generalized.
Hobart W, Walling, Richard D, Sontheimer
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Cutaneous lupus erythematosus (LE) may present in a variety of clinical forms. Three recognized subtypes of cutaneous LE are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE), and chronic cutaneous LE (CCLE). ACLE may be localized (most often as a malar or 'butterfly' rash) or generalized.
Hobart W, Walling, Richard D, Sontheimer
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Immunology of cutaneous lupus erythematosus
Clinics in Dermatology, 2004The cause and effect between ultraviolet light and cutaneous lupus erythematosus (CLE) is clear. In LE patients indeed, photosensitivity is one of the major diagnostic criteria of the systemic form of lupus erythematosus. This strong clinical association has led to the postulate that abnormal photosensitivity participates in the pathogenesis of ...
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Animal models of cutaneous lupus erythematosus and lupus erythematosus photosensitivity
Lupus, 1997Over the past decade, the most exciting and important finding in SLE-prone mice is the discovery of Fas/Fas ligand systems in the pathogenesis of autoimmune phenomena. A human model for murine lpr/gld disease has also been reported recently. Furthermore, as shown in Table 2, studies on Ig variable region genes, TCR genes and MHC class II genes have ...
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2008
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory autoimmune disorder, comprising a broad spectrum of clinical manifestations. Various environmental factors influence the clinical expression of CLE and a striking relationship has emerged between sunlight exposure and the various subtypes of this disease.
Annegret Kuhn +2 more
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Cutaneous lupus erythematosus (CLE) is a chronic inflammatory autoimmune disorder, comprising a broad spectrum of clinical manifestations. Various environmental factors influence the clinical expression of CLE and a striking relationship has emerged between sunlight exposure and the various subtypes of this disease.
Annegret Kuhn +2 more
openaire +1 more source