Results 101 to 110 of about 451,760 (295)

Radiation therapy for persistent or progressive mediastinal lymphoma after chemotherapy in FeLV‐positive cats: a retrospective case series of four cats

Australian Veterinary Journal, EarlyView.
Background Mediastinal lymphoma in feline leukaemia virus (FeLV)‐positive cats is associated with a poor prognosis, and therapeutic options may be limited when adequate disease control is not achieved with chemotherapy. The efficacy of radiation therapy in this setting has not been established.
A Uno, T Hasegawa, T Mori
wiley   +1 more source

Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation

Nature Communications
Primary cutaneous B-cell lymphoma encompass clinically heterogeneous entities. While primary cutaneous diffuse large B-cell lymphoma, leg type (pcDLBCL-LT) is aggressive, primary cutaneous follicle centre lymphoma (pcFCL) and primary cutaneous marginal ...
Johannes Griss, Sabina Gansberger, Inigo Oyarzun, Martin Simon, Mathias C. Drach, Vy Nguyen, Lisa E. Shaw, Ulrike Mann, Stefanie Porkert, Matthias Farlik, Wolfgang Weninger, Werner Dolak, Bertram Aschenbrenner, Beate M. Lichtenberger, Shawn Ziegler-Santos, Christine Wagner, Ingrid Simonitsch-Klupp, Stephan N. Wagner, Constanze Jonak, Patrick M. Brunner   +19 more
doaj   +1 more source

SAKK 35/14 randomized trial of rituximab with or without ibrutinib for patients with untreated follicular lymphoma

British Journal of Haematology, EarlyView.
Summary The randomized phase II SAKK 35/14 trial, conducted by the Swiss Group for Clinical Cancer Research (SAKK) and the Nordic Lymphoma Group (NLG), compared efficacy and safety of rituximab (375 mg/m2 intravenously for 4 weeks followed by maintenance every 2 months for 24 months) plus placebo (arm A) versus the same schedule of rituximab plus ...
Maria Cristina Pirosa, Marianne Brodtkorb, Sämi Schär, Björn E. Wahlin, Micaela Hernberg, Michael Pedersen, Anastasios Stathis, Thilo Zander, Urban Novak, Thorsten Zenz, Natalie Fischer, Fatime Krasniqi, Felicitas Hitz, Ann‐Sofie Johansson, David Löfgren, Peter Albert Meyer, Anne Turid Bjørnevik, Giulio Sartori, Stefanie Hayoz, Andrea Fuhrer, Luzia Steiner, Francesco Bertoni, Luca Ceriani, Stefan Dirnhofer, Emanuele Zucca, Bjørn Østenstad   +25 more
wiley   +1 more source

The antitumor mechanism of oclacitinib in canine lymphoma

Scientific Reports
Janus kinase (JAK) is a tyrosine kinase that binds to cytokine receptors and regulates transcription through signal transducer and activator of transcription (STAT) phosphorylation.
Miruki Harada, Sakuya Inanaga, Masashi Sakurai, Shusaku Shibutani, Takehito Sugasawa, Nobuo Murayama, Takafumi Osumi, Yuta Baba, Hiroki Sakai, Sadatoshi Maeda, Masaya Igase, Takuya Mizuno   +11 more
doaj   +1 more source

Myaesthenia Gravis associated with cutaneous lymphoma in a dog

, 2000
A middle-aged golden retriever presenting with exercise intolerance and multifocal cutaneous nodules was diagnosed as having non-epitheliotropic cutaneous lymphoma with concurrent myasthenia gravis.
S. M. Rhind, Munro, E.A.C., Hill, P.B., Rhind, SM, French, A.T., A. E. Ridyard, Ridyard, A.E., Rhind, S.M., French, AT, A. T. French, Hill, PB, P. B. Hill, Munro, EAC, Ridyard, AE, E. A. C. Munro   +14 more
core   +1 more source

Mogamulizumab efficacy on the skin compartment of cutaneous T‐cell lymphomas based on longitudinal analysis

British Journal of Haematology, EarlyView.
Summary Cutaneous T‐cell lymphoma is staged by the degree of skin, lymph node, viscera and blood involvement. Skin response is a determinant of treatment decisions. Mogamulizumab, an anti‐CC chemokine receptor 4 antibody, is approved for mycosis fungoides and Sézary syndrome after ≥1 systemic therapy.
Nobuaki Nakano, Kenta Murotani, Yoshito Ohya, Yukihiro Nishio   +3 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

Cutaneous lymphoma and chemokine

Japanese Journal of Clinical Immunology, 2011
The expression pattern of chemokines and chemokine receptors is specific to certain organs and cells. Therefore, chemokines are important to elucidate the mechanism of organ-specific human diseases such as cutaneous lymphoma, characterized by proliferation of clonally expanded lymphocytes in skin without detectable systemic involvement.
openaire   +3 more sources

SLAMF6 Enhances the Efficacy of Anti‐PD‐L1 Immunotherapy in CRC Through the STAT1/CXCL10 Signaling Axis

Cancer Science, EarlyView.
SLAMF6 recruits SHP‐2 to activate STAT1, upregulates CXCL10 and PD‐L1, promotes CD8+T cell infiltration, and enhances the efficacy of anti‐PD‐L1 therapy. ABSTRACT As a T‐cell receptor co‐stimulatory protein, signaling lymphocyte activation molecule family 6 (SLAMF6) is a member of the immune cell activating receptor family and is expressed on T cells ...
Yu Wu, Xinhui Lv, Shunhao Zhang, Yafang Chen, Sicong Liu, Feiyang Song, Chunmei Zhao, Guihua Wang, Xudong Wang   +8 more
wiley   +1 more source