Results 91 to 100 of about 451,760 (295)

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Primary cutaneous lymphoma of scalp in a child: a case report [PDF]

, 2017
Cutaneous lymphomas are a heterogenous group of lymphoproliferative disorders with involvement of skin and form a separate group under Non-Hodgkin’s lymphoma.
Lakshmi, A. Bhagya, Sri, K. Satya
core   +1 more source

A Response to “The Inverse Koebner Phenomenon in Cutaneous T‐Cell Lymphomas”

JEADV Clinical Practice, EarlyView.
Isabel Hariri, Alexander H. Enk, Jessica C. Hassel   +2 more
wiley   +1 more source

CD200 Expression in Folliculotropic Mycosis Fungoides Emerging During Dupilumab Treatment

The Journal of Dermatology, EarlyView.
ABSTRACT Folliculotropic mycosis fungoides (FMF) or mycosis fungoides with folliculotropism (MF‐F) is increasingly recognized in patients initially diagnosed with atopic dermatitis (AD) who subsequently worsen during dupilumab therapy. We report a case of FMF that became clinically apparent after dupilumab treatment.
Mai Tamaki, Hiroyuki Kusano, Tomomitsu Miyagaki, Ryoma Honda, Shinsuke Aida, Sohshi Morimura, Tomonori Takekoshi, Takayuki Shiomi, Toshihisa Hamada, Makoto Sugaya   +9 more
wiley   +1 more source

Primary cutaneous marginal-zone lymphoma [PDF]

, 2016
Primary cutaneous B cell lymphomas (PCBCL) are thesecond most common type of primary cutaneouslymphoma. The three main types of PCBCL areprimary cutaneous marginal-zone lymphoma(PCMZL), primary cutaneous follicle-centerlymphoma, and primary cutaneous ...
Farhadian, Joshua, Latkowski, Jo-Ann, Terushkin, Vtaly, Meehan, Shane A, Jo-Ann Latkowski, Shane A Meehan, Joshua Farhadian, Farhadian, Joshua ; Terushkin, Vtaly ; Meehan, Shane A ; Latkowski, Jo-Ann, Vtaly Terushkin   +8 more
core   +1 more source

Diffuse Skin Sclerosis in a Patient With Lung Cancer

JEADV Clinical Practice, EarlyView.
Anna‐Sophia Leven, Eva Hadaschik, Alpaslan Tasdogan   +2 more
wiley   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Radiographically Negative, Asymptomatic, Sentinel Lymph Node Positive Cutaneous T-Cell Lymphoma in a 3-Year-Old Male: A Case Report

Case Reports in Pediatrics, 2012
We present a case of a 3-year-old male originally diagnosed with a CD30+ anaplastic cutaneous T-cell lymphoma with no evidence of systemic disease after CT scan, PET scan, and bone marrow aspiration.
Jeffrey Carson, Jiri Bedrnicek, Shahab Abdessalam   +2 more
doaj   +1 more source

Nivolumab-Associated Cardiac Manifestation of Cutaneous T-Cell Lymphoma in a Patient With Concurrent Renal Cell Carcinoma

Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Cardiac involvement by cutaneous T-cell lymphoma is exceedingly rare and poses considerable diagnostic and therapeutic challenges. Immune checkpoint inhibitors targeting programmed cell death-1 have reported variable activity in T-cell lymphomas and have
Mohamed Ibrahim, DO, Nitya Batra, MBBS, Oluwatayo Adeoye, MD, Michael Acevedo Monsanto, MD, Ephraim Parent, MD, PhD, David Li, MD, Muhamad Alhaj Moustafa, MD, MS   +6 more
doaj   +1 more source

Primary Cutaneous T-Cell Lymphoblastic Lymphoma: Case Report and Literature Review

Case Reports in Hematology, 2019
Cutaneous involvement by precursor T-cell lymphoblastic leukemia/lymphoma (T-ALL/LBL) is rare, and almost all cases are seen in association with bone marrow, blood, and/or lymph node involvement.
Sharad Khurana, Manuel Beltran, Liuyan Jiang, Ernesto Ayala, Vivek Roy   +4 more
doaj   +1 more source