Results 71 to 80 of about 58,257 (262)

Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation

Nature Communications
Primary cutaneous B-cell lymphoma encompass clinically heterogeneous entities. While primary cutaneous diffuse large B-cell lymphoma, leg type (pcDLBCL-LT) is aggressive, primary cutaneous follicle centre lymphoma (pcFCL) and primary cutaneous marginal ...
Johannes Griss, Sabina Gansberger, Inigo Oyarzun, Martin Simon, Mathias C. Drach, Vy Nguyen, Lisa E. Shaw, Ulrike Mann, Stefanie Porkert, Matthias Farlik, Wolfgang Weninger, Werner Dolak, Bertram Aschenbrenner, Beate M. Lichtenberger, Shawn Ziegler-Santos, Christine Wagner, Ingrid Simonitsch-Klupp, Stephan N. Wagner, Constanze Jonak, Patrick M. Brunner   +19 more
doaj   +1 more source

Ultrasonography and MRI findings of cutaneous B-cell lymphoma, leg type

Journal of the Belgian Society of Radiology, 2011
We read the case report about imaging findings of cutaneous B-cell lymphoma in JBR-BTR with great interest (1). We would like to share ultrasonographic and magnetic resonance imaging (MRI) findings of our case with primary cutaneous B-cell lymphoma, leg ...
E Öztürk, S Sipahioglu, Ü Han, C Yücesoy, A Dilli, B Hekimog?lu   +5 more
doaj   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

The Journal of Pathology, EarlyView.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

Cutaneous lymphoma and chemokine

Japanese Journal of Clinical Immunology, 2011
The expression pattern of chemokines and chemokine receptors is specific to certain organs and cells. Therefore, chemokines are important to elucidate the mechanism of organ-specific human diseases such as cutaneous lymphoma, characterized by proliferation of clonally expanded lymphocytes in skin without detectable systemic involvement.
openaire   +3 more sources

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe, Kohei Yamakawa, Miyu Kobayashi, Yusuke Saigusa, Yukie Yamaguchi   +4 more
wiley   +1 more source

Demodex Infestation in Patients With Atopic Dermatitis Treated With Dupilumab: A Case–Control Study

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease in which dupilumab, an interleukin‐4 receptor alpha antagonist, has become a cornerstone therapy for moderate‐to‐severe disease. However, persistent facial and neck erythema and related symptoms have been increasingly reported during dupilumab treatment, and the underlying ...
Pinar Dursun, Ayse Nur Saribas Yildirim, Ayca Yazici   +2 more
wiley   +1 more source

Clinicopathological Profile of Cutaneous Lymphoma and Distinction of Early Mycosis Fungoides from Cutaneous Lymphoid Hyperplasia—A Retrospective Experience from Quaternary Care Centre in South India

Apollo Medicine
Introduction: Cutaneous lymphomas represent the second most common extra-nodal non-Hodgkin lymphoma. Mycosis fungoides (MF) is the most common primary cutaneous lymphoma.
N. Dhivya, R. Ashok Kumar
doaj   +1 more source

The Inverse Koebner Phenomenon in Cutaneous T‐Cell Lymphomas

JEADV Clinical Practice, EarlyView.
Alba Guglielmo, Corrado Zengarini, Alessandro Borghi, Alessandro Pileri   +3 more
wiley   +1 more source