Results 11 to 20 of about 756,649 (382)

Targeting the CD47-SIRPα Axis: Present Therapies and the Future for Cutaneous T-cell Lymphoma

Cells, 2022
The loss of CD47 on aging cells serves as a signal to macrophages to eliminate the target. Therefore, CD47 is a “do-not-eat-me” sign preventing macrophagal phagocytosis via interaction with its ligand SIRPα. Malignant lymphocytes of mycosis fungoides and
Amy Xiao, Oleg E. Akilov
doaj   +1 more source

Randomized phase 3 ALCANZA study of brentuximab vedotin vs physician’s choice in cutaneous T-cell lymphoma: final data

Blood Advances, 2021
Key Points Final ALCANZA data confirm more durable responses and longer PFS with brentuximab vedotin vs control in CD30+ cutaneous T-cell lymphoma. Brentuximab vedotin extended the time to next treatment vs physician's choice, suggesting that durable ...
S. Horwitz, J. Scarisbrick, R. Dummer, S. Whittaker, M. Duvic, Youn H. Kim, P. Quaglino, P. Zinzani, Oliver Bechter, H. Eradat, L. Pinter-Brown, O. Akilov, L. Geskin, J. Sanches, P. Ortiz-Romero, M. Weichenthal, D. Fisher, J. Walewski, J. Trotman, K. Taylor, S. Dalle, R. Stadler, J. Lisano, V. Bunn, M. Little, H. Prince   +25 more
semanticscholar   +1 more source

Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

Scientific Reports, 2021
T-cell non-Hodgkin’s lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin’s lymphoma to identify mutational ...
Christine L. Jones, A. Degasperi, V. Grandi, T. Amarante, John C. Prabhu Emma L. Marta Freya Jeanne M. Christophe Ambrose Arumugam Baple Bleda Boardman-Pretty Boiss, J. Ambrose, P. Arumugam, E. Baple, M. Bleda, F. Boardman-Pretty, J. Boissiere, C. Boustred, H. Brittain, M. Caulfield, G. Chan, C. Craig, L. Daugherty, A. de Burca, A. Devereau, G. Elgar, R. E. Foulger, T. Fowler, P. Furió-Tarí, A. Giess, J. Hackett, D. Halai, A. Hamblin, S. Henderson, J. Holman, T. Hubbard, K. Ibáñez, R. Jackson, L. J. Jones, D. Kasperaviciute, M. Kayikci, A. Kousathanas, L. Lahnstein, K. Lawson, S. Leigh, I. Leong, J. F. López, F. Maleady-Crowe, J. Mason, E. McDonagh, L. Moutsianas, Michael Mueller, N. Murugaesu, A. Need, P. O'donovan, C. Odhams, A. Orioli, C. Patch, M. B. Pereira, D. Perez-Gil, D. Polychronopoulos, J. Pullinger, T. Rahim, A. Rendon, P. Riesgo-Ferreiro, T. Rogers, M. Ryten, K. Savage, K. Sawant, R. Scott, A. Siddiq, A. Sieghart, D. Smedley, Katherine R. Smith, Samuel C. Smith, A. Sosinsky, W. Spooner, H. E. Stevens, A. Stuckey, R. Sultana, M. Tanguy, E. Thomas, S. Thompson, C. Tregidgo, A. Tucci, E. Walsh, S. Watters, M. Welland, E. Williams, K. Witkowska, S. Wood, M. Zarowiecki, T. Mitchell, S. Nik-Zainal, S. Whittaker   +88 more
semanticscholar   +1 more source

Cutaneous Lymphomas — Part II: Other Cutaneous Lymphomas

Actas Dermo-Sifiliográficas (English Edition), 2021
Primary cutaneous T-cell lymphomas other than mycosis fungoides, Sézary syndrome, and lymphoproliferative CD30+ disorders are few, accounting for less than 5% of all cutaneous lymphomas. A cytotoxic phenotype is characteristic of these tumors, and their clinical behavior is usually aggressive.
R M, Pujol, F, Gallardo
openaire   +2 more sources

Cutaneous Involvement of Extranodal NK/T Cell Lymphoma, Nasal Type, a Clinical and Histopathological Mimicker of Various Skin Diseases

Dermatopathology, 2022
Background: Extranodal NK/T cell lymphoma, nasal type (ENK/T) with cutaneous involvement has various histopathological findings and diverse clinical manifestations.
Preeyawat Ngamdamrongkiat, Sanya Sukpanichnant, Manasmon Chairatchaneeboon, Archrob Khuhapinant, Panitta Sitthinamsuwan   +4 more
doaj   +1 more source

Reliable blood cancer cells' telomere length evaluation by qPCR

Cancer Medicine, 2020
Background Telomere shortening is linked to a range of different human diseases, hence reliable measurement methods are needed to uncover such associations.
Joana Ropio, Alain Chebly, Jacky Ferrer, Martina Prochazkova‐Carlotti, Yamina Idrissi, Lamia Azzi‐Martin, David Cappellen, Anne Pham‐Ledard, Paula Soares, Jean‐Philippe Merlio, Edith Chevret   +10 more
doaj   +1 more source

Investigating a fast-growing nodule on the face: A case of primary cutaneous marginal zone lymphoma [PDF]

Journal of Krishna Institute of Medical Sciences University, 2022
Primary cutaneous B-cell lymphomas are non-Hodgkin lymphomas that present in the skin without evidence of extracutaneous involvement at diagnosis. There are three types of primary cutaneous B-cell lymphomas: primary cutaneous marginal zone lymphoma ...
N. Ashok Kumar, Sane Roja Renuka, C. Geo Danny , Richa Jotwani   +3 more
doaj  

Primary Cutaneous B-Cell Lymphoma: An Update on Pathologic and Molecular Features

Hemato, 2022
Primary cutaneous B-cell lymphomas (PCBCLs) account for 25% of all primary cutaneous lymphomas. Three major types are currently recognized by the WHO classification: primary cutaneous marginal zone B-cell lymphoma (PCMZL), primary cutaneous follicle ...
Marco Lucioni, Sara Fraticelli, Giuseppe Neri, Monica Feltri, Giuseppina Ferrario, Roberta Riboni, Marco Paulli   +6 more
doaj   +1 more source

Long-term Therapeutic Success of Intravenous Rituximab in 26 Patients with Indolent Primary Cutaneous B-cell Lymphoma

Acta Dermato-Venereologica, 2021
Systemic monotherapy with rituximab is a well-known treatment approach for primary cutaneous follicle centre lymphoma and primary cutaneous marginal zone lymphoma. Both have excellent prognosis despite high relapse rates.
Stefanie Porkert, Pamela Mai, Constanze Jonak, Felix Weihsengruber, Klemens Rappersberger, Wolfgang Bauer, Ingrid Simonitsch-Klupp, Markus Raderer, Julia Valencak   +8 more
doaj   +1 more source

Epidemiological, anatomopathological, and immunophenotypical aspects of cutaneous lymphomas in dogs

Pesquisa Veterinária Brasileira, 2023
: Cutaneous lymphomas are uncommon tumors in dogs that can occur as epitheliotropic and non-epitheliotropic types. The epitheliotropic type comprises three, already well established, distinct clinicopathological presentations.
Renata D. Mazaro, Douglas M. Lorenzetti, Suzana M.G. Leite, Eduardo K. Masuda, Leonardo D. Da Costa, Rosemeri O. Vasconcelos, Antonio Flávio M. Dantas, Luciana C. Lacerda, Tereza Cristina Da Silva, Marco Aurélio A. Motta, Bruno Cogliati, Rafael A. Fighera   +11 more
doaj   +1 more source