Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source
Enigmatic Presentation of Primary Cutaneous Lymphoma in a Boy. [PDF]
Farhan A, Fakhro A, Burshaid D.
europepmc +1 more source
A retrospective review of cutaneous lymphoma in Botswana. [PDF]
Rodriguez O +7 more
europepmc +1 more source
Systematic review (51 studies; 547 patients) indicates dupilumab may unmask/worsen CTCL (mainly MF/SS). A French Delphi consensus recommends rigorous diagnostic workup, avoiding dupilumab in confirmed CTCL, discontinuing upon diagnosis, and favouring methotrexate or phototherapy.
Florent Amatore +8 more
wiley +1 more source
Is Kaposi sarcoma a novel comorbidity of cutaneous lymphoma? A systematic review of the literature. [PDF]
Moritz RKC +5 more
europepmc +1 more source
Mycosis Fungoides with Dermal Mucin Deposition: An Unusual Variant of the Most Challenging Primary Cutaneous Lymphoma. [PDF]
Filosa A +7 more
europepmc +1 more source
Medical Phototherapy Malpractice and Legal Precedents in North America (1983–2025)
International Journal of Dermatology, EarlyView.
Ghassan Barnawi +6 more
wiley +1 more source
OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta +4 more
wiley +1 more source
Corrigendum: Exploring the educational needs of patients with cutaneous lymphoma using an educational needs assessment tool. [PDF]
Ivert LU +3 more
europepmc +1 more source
Granuloma annulare: not as simple as it seems. [PDF]
Parish, Lawrence Charles +1 more
core +1 more source

