Integrative epidemiology and immunotranscriptomics uncover a risk and potential mechanism for cutaneous lymphoma unmasking or progression with dupilumab therapy. [PDF]
Cabrera-Perez JS +7 more
europepmc +1 more source
Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast +22 more
wiley +1 more source
Exploring the educational needs of patients with cutaneous lymphoma using an educational needs assessment tool. [PDF]
Ivert LU +3 more
europepmc +1 more source
Treatment of early-stage mycosis fungoides: results from the PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) study. [PDF]
Quaglino P +66 more
europepmc +1 more source
Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source
Significant survival disparity in Black patients with cutaneous lymphoma: a retrospective cohort study. [PDF]
Trum NA +4 more
europepmc +1 more source
Systematic review (51 studies; 547 patients) indicates dupilumab may unmask/worsen CTCL (mainly MF/SS). A French Delphi consensus recommends rigorous diagnostic workup, avoiding dupilumab in confirmed CTCL, discontinuing upon diagnosis, and favouring methotrexate or phototherapy.
Florent Amatore +8 more
wiley +1 more source
Independent evolution of cutaneous lymphoma subclones in different microenvironments of the skin. [PDF]
Iyer A +6 more
europepmc +1 more source

