Results 221 to 230 of about 451,760 (295)

Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges

MedComm, Volume 7, Issue 11, November 2026.
Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu, Guangming Tu, Chao Wang, Hongyan Zhao, Ziyi Wu, Wei Li, Li Chen, Bailin Niu   +7 more
wiley   +1 more source

Regulatory T Cells in Health and Disease

MedComm, Volume 7, Issue 11, November 2026.
Regulatory T cells (Tregs) arise through distinct developmental pathways and adapt to specialized tissue niches to maintain immune tolerance, barrier integrity, and metabolic homeostasis. In disease, Tregs undergo context‐dependent changes, ranging from functional insufficiency and lineage instability in autoimmune, inflammatory, cardiovascular, and ...
Mingyi Li, Si Zhang, Tangchun Wu, Tingting Tang, Xiang Cheng   +4 more
wiley   +1 more source

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

MedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang, Qifei Pan, Wenjuan Long, Xinyao Li, Jianqin Mao, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Mingqin Shi, Yang Zhou, Jiarong Du, Zhongyang Hu, Xiaoman Lv, Yishu Chen, Dongdong Qin   +15 more
wiley   +1 more source

Safety, Efficacy, and Pharmacokinetics of Unecritinib (TQ‐B3101) in Pediatric Patients With Relapsed/Refractory Anaplastic Lymphoma Kinase‐Positive Anaplastic Large‐Cell Lymphoma: A Phase I Study

MedComm, Volume 7, Issue 11, November 2026.
This Phase I study evaluated unecritinib (TQ‐B3101) in pediatric patients with relapsed/refractory ALK+ anaplastic large‐cell lymphoma. Unecritinib showed a manageable safety profile without dose‐limiting toxicities and achieved remarkable efficacy, with a 100% overall response rate.
Suying Lu, Junting Huang, Ruiqing Cai, Yan Gao, Jia Zhu, Juan Wang, Yi Que, Zijun Zhen, Feifei Sun, Huiqiang Huang, Yizhuo Zhang   +10 more
wiley   +1 more source

Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Varicella zoster virus (VZV) and herpes simplex virus (HSV) are major causes of viral meningitis and encephalitis. Standard intermittent intravenous acyclovir requires hospitalisation, reducing patient comfort and prolonging admissions. Continuous infusion may maintain therapeutic plasma and cerebrospinal fluid (CSF) concentrations while ...
Irene G. Manders, Eline L. van Tuinen, Martijn Weisfelt, Marco Goeijenbier, Jayant S. Kalpoe, Steven F. L. van Lelyveld, Eric C. M. van Gorp, Ken Ho Hua   +7 more
wiley   +1 more source

Inflammatory Pseudotumour in Common Seal (Phoca vitulina): A Case Report

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A 19‐year‐old intact male common seal (Phoca vitulina) diagnosed with a chronic ulcer. Microbiology identified Vibrio alginolyticus. Radiography noted phalanx alterations. Macroscopic, histopathological, and immunohistochemical examinations revealed a neoplastic origin with a myofibroblastic phenotype. This report describes the first documented case of
Javier M. De Pablo‐Moreno, Rocío Canales, Mireia Mainez, Nicolás Aradilla, Blanca Chinchilla, Néstor Porras, Ignacio Vargas‐Castro, Antonio Rodríguez‐Bertos   +7 more
wiley   +1 more source

Rare Feline Gingival Extramedullary Plasmacytoma: Clinical Application of Electrochemotherapy for Local Control

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
This case report describes an aggressive gingival extramedullary plasmacytoma (EMP) with regional lymph node metastasis in a 14‐year‐old cat. As complete surgical excision was unfeasible, three weekly electrochemotherapy (ECT) sessions using intravenous bleomycin were performed for local tumour control.
Seulgi Hwang, Hayoung Ryu, Dong‐In Jung, DoHyeon Yu, Kyu‐Woan Cho, Hyeona Bae   +5 more
wiley   +1 more source

Idiopathic immune‐mediated polyarthritis in a dog associated with ionised hypercalcaemia and probable ischaemic dermatopathy

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 5‐year‐old, spayed, female Shiba Inu was presented with a 6‐week history of reduced appetite, lethargy and generalised stiffness, which showed only limited improvement despite anti‐inflammatory treatment. The most significant clinical abnormalities were pyrexia, stiffness, pain on joint manipulation and cutaneous lesions. Laboratory findings
Jeanne Bergeat, Eddy Nassif, Sarah Berger, Isabelle Lagrange, Noëlle Cochet‐Faivre, Pierre Deshuillers, Maxime Kurtz   +6 more
wiley   +1 more source