Results 71 to 80 of about 110,182 (337)

Molluscum contagiosum infection with features of primary cutaneous anaplastic large cell lymphoma [PDF]

open access: yes, 2019
CD30+ T cell pseudolymphomas (CD30+ PSL) are a group of benign inflammatory cutaneous disorders that can develop in settings of viral infections or drug reactions.
Lee, Jason B   +3 more
core   +1 more source

Identification of human papillomavirus DNA in cutaneous lesions of Cowden syndrome [PDF]

open access: yes, 2003
Background: Cowden syndrome (CS) or multiple hamartoma syndrome is a cancer-associated genodermatosis inherited in an autosomal dominant pattern. One of the diagnostic criteria is facial papules which are felt to be trichilemmomas, benign hair follicle ...
Burgdorf, Walter H. C.   +4 more
core   +1 more source

Synthesis, In Silico, and Biological Evaluation of Non‐Hydroxamate Benzoic Acid–Based Derivatives as Potential Histone Deacetylase Inhibitors (HDACi)

open access: yesChemistry &Biodiversity, EarlyView.
Compound A3bn exhibited strong binding affinities for HDAC2, HDAC6, and HDAC8. A3bn’s anticancer IC50 values were similar to those of SAHA. Cell death resulted from the extrinsic apoptotic pathway. Compound A3bn, a hydrophilic linker, which promotes zinc coordination, may be the cause of its increased activity across HDAC isoforms. ABSTRACT Unregulated
Nedaa A. Abd Al Rahim   +8 more
wiley   +1 more source

Somatostatin receptor scintigraphy in cutaneous malignant lymphomas [PDF]

open access: yes, 1996
Background: Lymphoid cells may express somatostatin receptors (SS-Rs) on their cell surface. Therefore radiolabeled somatostalin analogues may be used to visualize SS-R-positive lymphoid neoplasms in vivo.
Anker-Lugtenburg, P.J. (P.) van den   +6 more
core   +1 more source

Harnessing Synergies between Combinatorial Microfluidics and Machine Learning for Chemistry, Biology, and Fluidic Design

open access: yesChemistry–Methods, EarlyView.
This review explores the synergy of combinatorial microfluidics and machine learning, highlighting their transformative impact on high‐throughput experimentation, closed‐loop reaction optimization, and autonomous platform development. Key applications in chemical synthesis, biological research, and microfluidic design are discussed, addressing ...
Suyash S. Damir   +3 more
wiley   +1 more source

Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer [PDF]

open access: yes, 2019
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, incurable cancer with a 20% 1 year survival rate. While standard-of-care therapy can prolong life in a small fraction of cases, PDAC is inherently resistant to current treatments, and novel ...
Adile, Ashley A.   +19 more
core   +3 more sources

Cutaneous T-cell Lymphoma [PDF]

open access: yesClinics in Laboratory Medicine, 2017
Cutaneous T-cell lymphomas comprise a heterogeneous group of diseases characterized by monoclonal proliferations of T lymphocytes primarily involving skin, modified skin appendages, and some mucosal sites. This article addresses the basic clinical, histologic, and immunohistochemical characteristics of this group of diseases, with additional attention ...
openaire   +3 more sources

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia   +4 more
wiley   +1 more source

Update on primary cutaneous T-cell lymphomas rare subtypes

open access: yesDermatology Reports
Rare subtypes of cutaneous T-cell lymphomas (CTCL) include four entities, primary cutaneous γδ T-cell lymphoma, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, and primary cutaneous CD4+ small/medium T-cell ...
Silvia Alberti-Violetti, Emilio Berti
doaj   +1 more source

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