Citotoxicidade de derivados maleimídicos: relação entre a atividade antitumoral e antiadipogênica [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.O câncer é caracterizado pelo crescimento descontrolado de células que invadem o tecido circundante e
Rosolen, Daiane
core
Cutaneous metastases from malignant melanoma: clinical features and new therapeutic perspectives
, 2011 In this chapter, cutaneous metastases from malignant melanoma will be analyzed from a clinical and a prognostic point of view. This non rare condition is often distressing for the patient, as cutaneous lesions increase progressively in number and size
Paola Savoia +6 more
core +1 more source
Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He +11 more
wiley +1 more source
Cutaneous Malignant Melanoma with Testicular Metastases in a Wild Rabbit (Oryctolagus cuniculus). [PDF]
Vet Sci, 2023 Abbate JM +4 more
europepmc +1 more source
Canadian family physician Medecin de famille canadien, 2012 In Canada melanoma causes 400 deaths a year, often in young adult patients. Excessive ultraviolet radiation to unprotected skin is an important cause. Certain moles should be removed as a precautionary measure; an experienced clinician can recognize many melanomas.
S T, Norvell, A J, Bodurtha
openaire +1 more source
Malignant Melanoma of Nose and Paranasal Sinuses: 2 Case Reports
, 2010 Malignant melanoma is one of the rare and highly aggressive diseases of the sinonasal cavity. High index of suspicion is required for diagnosis as the patient usually presents with non specific signs and symptoms.
Gupta, N +9 more
core
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Introduction Preferentially expressed antigen in melanoma (PRAME) immunohistochemistry helps distinguish non‐acral melanocytic lesions, but few studies have addressed its value in acral lesions. We aimed to identify an optimal PRAME cut‐off score to differentiate acral melanoma (AM) from acral melanocytic nevi (AMN).
Kritsada Phatcharamaneepakorn +4 more
wiley +1 more source
Predicting cutaneous malignant melanoma patients' survival using deep learning: a retrospective cohort study. [PDF]
J Cancer Res Clin Oncol, 2023 Cai S, Li W, Deng C, Tang Q, Zhou Z.
europepmc +1 more source
Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling
Cytopathology, EarlyView.Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu +3 more
wiley +1 more source
Thyroid dysfunction and risk of cutaneous malignant melanoma: a bidirectional two-sample Mendelian randomization study. [PDF]
Front Endocrinol (Lausanne), 2023 Dong H +6 more
europepmc +1 more source