SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley +1 more source
Trends in Survival and Cure Indicators of Thin and Thick Cutaneous Malignant Melanoma in Italy. [PDF]
Mancini S +26 more
europepmc +1 more source
Genetic Characteristics of Primary Cutaneous Malignant Melanoma in Koreans Compared With Western Populations. [PDF]
Jang H, Ryu HJ, Kim SK.
europepmc +1 more source
The epidemiology of cutaneous malignant melanoma in Nova Scotia
Andrew Howlett, Ron AD Dewar
openalex +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
A bibliometric systematic review of extracellular vesicles in cutaneous malignant melanoma from 2005 to 2025. [PDF]
Christodoulides N +4 more
europepmc +1 more source
Lnc-PKNOX1-1 inhibits tumor progression in cutaneous malignant melanoma by regulating NF-κB/IL-8 axis. [PDF]
Hong A +9 more
europepmc +1 more source
Cutaneous Metastases from Malignant Melanoma: Clinical Features and New Therapeutic Perspectives
Paola Savoia, Paolo Fava, Maria Grazia
openalex +2 more sources
COPS8 in cutaneous melanoma: an oncogene that accelerates the malignant development of tumor cells and predicts poor prognosis [PDF]
Liangliang Sun
openalex +1 more source
Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
wiley +1 more source

