Results 171 to 180 of about 87,940 (259)

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak   +2 more
wiley   +1 more source

The Effects of Biologic Agents on Carotid Intima‐Media Thickness and Hepatic Steatosis in Patients With Moderate‐To‐Severe Psoriasis: A Prospective Observational Cohort Study

open access: yesJEADV Clinical Practice, EarlyView.
In this prospective observational cohort study, 34 patients with moderate‐to‐severe psoriasis received biologic therapy (anti‐TNF‐α, anti‐IL‐12/23, or anti‐IL‐17) for 6 months. Carotid intima–media thickness decreased significantly in the overall cohort (p < 0.01), with the greatest reductions in the anti‐IL‐17 and anti‐IL‐12/23 groups.
Harika Ödemiş   +6 more
wiley   +1 more source

Cutaneous Manifestations in Patients with Dermatomyositis, Are They Only Skin Deep? [PDF]

open access: yesDermatol Ther (Heidelb)
McKee S   +6 more
europepmc   +1 more source

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