Results 121 to 130 of about 5,369,336 (287)

Diagnostic Delay of Unilateral Facial Paralysis Caused by Occult Malignancy: A Scoping Review

The Laryngoscope, EarlyView.
This scoping review of 27 studies (66 patients) characterizes unilateral facial paralysis caused by occult malignancy, a rare entity marked by a mean diagnostic delay of 21 months and initially negative imaging in 89% of cases. Progressive paralysis, lack of recovery, trigeminal or additional cranial nerve involvement, and a history of regional skin ...
Kai C. Kokesh, Gabrielle Cahill, Irene Kim, Babak Azizzadeh, G. Nina Lu   +4 more
wiley   +1 more source

Contemporary Treatment Patterns in Surgically Treated Temporal Bone Cancer

The Laryngoscope, EarlyView.
In a national cohort of 811 surgically treated temporal bone cancer patients, adjuvant radiation therapy was the most frequently utilized postoperative treatment (20.3%), while chemotherapy and immunotherapy were used far less frequently. Multimodal treatment, particularly combined parotidectomy and neck dissection, was strongly associated with higher ...
Raquel Rowell, Christopher Z. Wen, Vera Bzhilyanskaya, Jane Y. Tong, Adam C. Kaufman   +4 more
wiley   +1 more source

EHR‐Integrated Synoptic Operative Reporting for Head and Neck Oncologic Surgery

The Laryngoscope, EarlyView.
EHR‐integrated synoptic operative templates for head and neck oncologic surgery was developed and implemented at a tertiary academic cancer center. Departmental adherence rose from 49% to nearly 80% over 6 months, and 94.5% of reviewed cases met targets for complete, internally consistent documentation. The resulting structured data dictionary provides
Miriam N. Lango, Avery Sinnathamby, Marc‐Elie Nader, Paul W. Gidley, Karen Y. Choi, Mark Zafereo, Carly E. A. Barbon, Kristen B. Pytynia, Anastasios Maniakas, Amy Hessel, Ryan P. Goepfert, Faisal I. Ahmad, Jennifer L. Anderson, Sahil K. Kapur, Jolyn S. Taylor   +14 more
wiley   +1 more source

CIT tumor lines: A series of immunogenic murine cutaneous squamous cell carcinoma cell lines derived from chemical carcinogenesis

JID Innovations
Immunotherapy is widely used to treat advanced-stage skin cancer, but it is effective for only approximately half of patients with skin cancer. To overcome current barriers, preclinical mouse models that faithfully recapitulate the genetics, mutation ...
Robert Letchworth, Miho Tanaka, Alina A. Barnes, Lotus Lum, Savannah Hughes, Grant Schlauderaff, Piyush Chaudhary, Kenneth M. Ng, Daphne Superville, Jadyn Leek, Joshua Tay, Corinna Martinez Luna, Maria Gonzalez, Eric Smith, Dekker C. Deacon, Allie Grossmann, Melissa Q. Reeves   +16 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Expression and regulation of N-Myc Downstream- Regulated gene 1 in squamous cell carcinoma of the oesphagus [PDF]

, 2009
Squamous cell carcinoma of the oesophagus is a formidable disease which poses a significant health risk in developing countries where the incidence is frequently high and access to health care facilities is often limited.
Bracher, Jacqueline Claire
core   +1 more source

The FOXQ1/SSBP2 Regulatory Axis Drives Malignant Progression of Melanoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Melanoma is a highly aggressive skin cancer with poor prognosis, often linked to excessive UV exposure. Despite advancements in immunotherapy and targeted treatments, melanoma's invasiveness and metastatic potential remain significant challenges.
Xiaoyu Zhang, Yu Hou, Jiahui Liu, Yuehua Han, Jiangang Feng   +4 more
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Exposed Necrotic Bone in a Head and Neck Cancer Patient: Report of a Diagnostic Challenge

Diagnostics
Background and Clinical Significance: The current study aims to show the diagnostic challenge of mandibular exposed necrotic bone in a patient with locally aggressive cutaneous squamous cell carcinoma of the lower lip and carrying risk factors for ...
Fabio Dell’Olio, Rosaria Arianna Siciliani, Marta Forte, Saverio Capodiferro, Gianfranco Favia, Luisa Limongelli   +5 more
doaj   +1 more source