Results 241 to 250 of about 51,662 (290)

Diagnostic utility and pitfalls of human T‐lymphotropic virus serology in adult T‐cell leukemia/lymphoma: evidence from a 25‐year pathology‐based nonendemic cohort

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract Adult T‐cell leukemia/lymphoma (ATLL) is a distinct type of peripheral T‐cell lymphoma (PTCL) driven by human T‐lymphotropic virus type I (HTLV‐1)–infected T cells, but diagnosis can be confounded by histological overlap with non‐ATLL PTCL. While molecular testing is the diagnostic gold standard in endemic areas, HTLV‐1/2 serology is often ...
Chang‐Tsu Yuan   +10 more
wiley   +1 more source

Dacarbazine as a Positive Control in Melanoma Cell Lines (A375, SK‐MEL‐103, 1205Lu) and a Human Ex Vivo Skin Model

open access: yesAdvanced Biology, Volume 10, Issue 1, January 2026.
The work seeked to demonstrate the drug Dacarbazine as a positive control for toxicity tests in immortalized skin cells (keratinocytes and fibroblasts) and in different neoplastic cell lines, through the assay with resazurin. In addition, an alternative model to replace animals in experimental studies, using skin explant culture (hOSEC ‐ human ...
Marcel Nani Leite   +6 more
wiley   +1 more source

Impact of Hyaluronic Acid on the Cutaneous T-Cell Lymphoma Microenvironment: A Novel Anti-Tumor Mechanism of Bexarotene. [PDF]

open access: yesCancers (Basel)
Ikawa T   +7 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Nanopore Sequencing for T-Cell Receptor Rearrangement Analysis in Cutaneous T-Cell Lymphoma. [PDF]

open access: yesCancers (Basel)
Cieslak C   +8 more
europepmc   +1 more source

Light Metabolically Reprograms CD8+ T Cells to Potentiate STING‐Driven Tumor Eradication and Prevent Metastasis

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Low‐level light (LLL) rejuvenates exhausted CD8+ T cells, boosting STING‐driven tumor eradication and prevents metastasis. NanoSTING@Mn enhances CD8+ T cells infiltration while LLL restores its function expanding to progenitor‐exhausted cells. These cells form central memory T cells in lymphoid organs. Intranasal nanoSTING@Mn redirects antitumor CD8+ T
Asmita Banstola   +9 more
wiley   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Potential mogamulizumab-associated inflammatory bowel disease in cutaneous T-cell lymphoma management. [PDF]

open access: yesJAAD Case Rep
Blanchard G   +6 more
europepmc   +1 more source

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