Results 131 to 140 of about 59,265 (270)
Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions
MedComm, Volume 7, Issue 3, March 2026.Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu +9 more
wiley +1 more source
Natural history of a visceral leishmaniasis outbreak in highland Ethiopia [PDF]
, 2009 In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the
Alvar, J +14 more
core +1 more source
Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.Histological and Immunohistochemical Characterization of a Histiocytic Sarcoma Associated with a Follicular Lymphoma in a Ring‐tailed Lemur (Lemur catta). Nicolás Aradilla, Rocío Canales, Teresa Lorenzo‐Bermejo, Mireia Mainez, Jordi Aguiló‐Gisbert, David Marbella, Javier María De Pablo‐Moreno and Antonio Rodríguez‐Bertos.
Nicolás Aradilla +7 more
wiley +1 more source
Annals of Saudi Medicine, 2011 Background and Objectives: There are few reports of cutaneous tuberculosis with immunosuppressed states such as HIV, use of immunosuppressants or malignancy.
Varshney Anupam, Goyal Tarang
doaj
WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.Myeloid‐derived suppressor cells (MDSCs) are key contributors to cancer immunotherapy failure and major targets in new therapeutic strategies. We highlight therapeutic approaches to counteract their immunosuppressive functions and discuss recent efforts to optimize drug delivery for controlling MDSCs, focusing on resiquimod as a representative drug ...
Yanying He, Yoon Yeo
wiley +1 more source
Review of Herpes Zoster Occurrence in Patients With Atopic Dermatitis Treated With JAK Inhibitors
Clinical and Translational Science, Volume 19, Issue 3, March 2026.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease that markedly impairs quality of life. Janus kinase inhibitors (upadacitinib, abrocitinib, and baricitinib) are effective therapies for moderate‐to‐severe AD but are associated with viral reactivation, particularly herpes zoster (HZ), due to immunosuppressive effects on interferon ...
Anna Mandecka +7 more
wiley +1 more source
Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
, 1987 We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core