Results 91 to 100 of about 70,792 (305)

Drought-responsive ZmFDL1/MYB94 regulates cuticle biosynthesis and cuticle-dependent leaf permeability [PDF]

, 2020
In all land plants, the outer surface of aerial parts is covered by the cuticle, a complex lipid layer that constitutes a barrier against damages caused by environmental factors and provides protection against non-stomatal water loss.
David Stephen Horner, Domergue, Frédéric, Massimo Zilio, Frédéric Domergue, Valentina Ricciardi, Persico, Martina, Chiara, Matteo, Zilio, Massimo, Matteo Chiara, Gabriella Consonni, Ricciardi, Valentina, Martina Persico, Giulia Castorina, Castorina, Giulia, Horner, David Stephen, Consonni, Gabriella   +15 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Distribution of the Nerves in the Cuticle [PDF]

The Journal of Nervous and Mental Disease, 1876
n ...
openaire   +1 more source

STUDIES ON ARTHROPOD CUTICLE. II. ELECTRON MICROSCOPE STUDIES OF EXTRACTED CUTICLE,,

The Biological Bulletin, 1948
1. Chitin purifications alter the structure of cuticular membranes of insects more or less extensively.2. Our data agree with the x-ray diffraction studies of Fraenkel and Rudall in showing:(a) The cuticle cannot be viewed as a rigid chitin framework iii the interstices of which other components are deposited.(b) Protein extraction methods have no ...
Richards, A. Glenn (Albert Glenn), Korda, Frances H   +1 more
openaire   +4 more sources

Matrix dynamics during assembly of the first pre-cuticle and cuticle.

, 2023
C. elegans embryos expressing functional pre-cuticle (A-B) or cuticle collagen (C-D) fusion proteins from endogenously-tagged loci. A) noah-1(mc68 [NOAH-1::mCherry(int)]). B) lpr-3(cs250 [ss::SfGFP::LPR-3]). C) dpy-17(syb3685 [DPY-17::mNG]).
Jennifer D. Cohen (2902514), John I. Murray (17002272), Alexandra Belfi (13242947), Susanna K. Birnbaum (17002269), Jennifer R. G. Adams (17002275), Andrew D. Chisholm (7851476), Meera V. Sundaram (2902509)   +6 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

New insights into the properties of pubescent surfaces: peach fruit as model

, 2011
The surface of peach (Prunus persica ‘Calrico’) is covered by a dense indumentum, which may serve various protective purposes. With the aim of relating structure to function, the chemical composition, morphology, and hydrophobicity of the peach skin was ...
Domínguez, Eva, Khayet Souhaimi, Mohamed, Fernandez Fernandez, Victoria, Liakoloulos, Georgios, Pablo Montero-Prado, Domínguez-Carmona, Eva María, Georgios Liakopoulos, Heredia-Guerrero, José A., Mohamed Khayet, Víctor del Río, Tacchini, Ignacio, Heredia, Antonio, Karabourniotis, George, Val, Jesús, José Alejandro Heredia-Guerrero, Jesús Val, Val Falcón, Jesús, Fernández, Victoria, Khayet, Mohamed, George Karabourniotis, Victoria Fernández, Heredia-Guerrero, Jose Alejandro, Rio, Victor del, Montero Prado, Pablo, Montero-Prado, Pablo, Liakopoulos, Georgios, Antonio Heredia, Cristina Nerín, Nerín, Cristina, Heredia Guerrero, José Alejandro, Ignacio Tacchini, Eva Domínguez   +31 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Biochemical analysis of Caenorhabditis elegans surface mutants

, 1997
A collection of Caenorhabditis elegans mutants that show ectopic surface lectin binding (Srf mutants) was analyzed to determine the biochemical basis for this phenotype. This analysis involved selective removal or labeling of surface components, specific
Silverman, M., Link, C., Blaxter, M.L.
core  

Major metabolites in cuticle.

, 2013
(A) Relatively abundant polar metabolites in cuticle. Data are presented as a heat-map of peak areas, from red (>2×107) to blue (1×107) to blue (
David G. Watson (173640), Venkateswara R. Chintapalli (173625), Julian A. T. Dow (173652), Dominika Korzekwa (477649), Mohammed Al Bratty (173636)   +4 more
core   +1 more source